Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 2/20 | 0.64 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7220934 | 1.00 | ENPP3 (0.64) | ENPP3ENPP1CA1CA2HDAC6 | |
| SCHEMBL16378628 | 0.88 | ENPP3 (0.70) | ENPP3ENPP1CA1CA2HDAC6 | |
| SCHEMBL7221412 | 0.88 | ENPP3 (0.62) | ENPP3ENPP1HDAC6HDAC1HDAC8 | |
| SCHEMBL7215190 | 0.88 | ENPP3 (0.70) | ENPP3ENPP1CA1CA2HDAC6 | |
| SCHEMBL16199782 | 0.88 | CA1 (0.56) | ENPP3ENPP1CA1CA2HDAC6 | |
| SCHEMBL12243296 | 0.87 | NPC1 (0.50) | ENPP3ENPP1HDAC6HDAC1HDAC8 | |
| SCHEMBL1000268 | 0.86 | RAB9A (0.51) | ENPP3ENPP1HDAC6HDAC1HDAC8 | |
| SCHEMBL7221944 | 0.86 | ALDH1A1 (0.54) | ENPP3ENPP1HDAC6HDAC1HDAC8 | |
| SCHEMBL7217142 | 0.86 | ENPP3 (0.48) | ENPP3ENPP1CA1CA2HDAC6 | |
| SCHEMBL8399604 | 0.85 | ENPP3 (0.84) | ENPP3ENPP1HDAC6HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8921309-B2 | Lipopeptide compounds and their use | UNIQUEST PTY LIMITED (AU) | 2014-12-30 | — | — | US | disclosed |