Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16154469 | 0.84 | CYP2A6 (0.43) | TDP1ALDH1A1MAPTGAAMAOA | |
| SCHEMBL14944395 | 0.80 | MAPT (0.47) | TDP1ALDH1A1MAPTGAAMAOA | |
| SCHEMBL23967969 | 0.80 | MAPT (0.42) | TDP1ALDH1A1POLBMAPTGAA | |
| SCHEMBL25878367 | 0.77 | TRPA1 (0.50) | TDP1ALDH1A1POLBMAPTGAA | |
| SCHEMBL31673873 | 0.76 | POLB (0.55) | ALDH1A1POLBMAPTTDP2NSD2 | |
| SCHEMBL23854312 | 0.76 | POLB (0.55) | ALDH1A1POLBMAPTTDP2NSD2 | |
| SCHEMBL19217642 | 0.76 | MAOA (0.41) | TDP1ALDH1A1MAPTGAAMAOA | |
| SCHEMBL16852393 | 0.75 | GRM2 (0.37) | TDP1ALDH1A1POLBTDP2NSD2 | |
| SCHEMBL29438559 | 0.74 | — | — | |
| SCHEMBL79908 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2352061-B1 | ORIENTATION FILM, LIQUID CRYSTAL DISPLAY HAVING ORIENTATION FILM, AND METHOD FOR FORMING ORIENTATION FILM | SHARP KK (JP) | 2015-01-07 | — | — | EP | disclosed |