Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31547677 | 0.84 | TDP1 (0.52) | MAPTGAATDP1ALDH1A1TP53 | |
| SCHEMBL3043421 | 0.84 | TDP1 (0.52) | MAPTGAATDP1ALDH1A1TP53 | |
| SCHEMBL25878367 | 0.82 | TRPA1 (0.50) | MAPTGAATDP1ALDH1A1TP53 | |
| SCHEMBL31673873 | 0.82 | POLB (0.55) | MAPTALDH1A1POLBTDP2NSD2 | |
| SCHEMBL23854312 | 0.82 | POLB (0.55) | MAPTALDH1A1POLBTDP2NSD2 | |
| SCHEMBL16378659 | 0.80 | TDP1 (0.37) | MAPTGAATDP1ALDH1A1TP53 | |
| SCHEMBL16852393 | 0.80 | GRM2 (0.37) | TDP1ALDH1A1TP53POLBTDP2 | |
| SCHEMBL20076409 | 0.80 | LMNA (0.50) | MAPTGAATDP1ALDH1A1TP53 | |
| SCHEMBL29038580 | 0.79 | MAPT (0.48) | MAPTGAATDP1ALDH1A1TP53 | |
| SCHEMBL26968681 | 0.74 | LMNA (0.54) | MAPTGAATDP1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3481916-B1 | ELECTRONIC SWITCH | MERCK PATENT GMBH (DE) | 2021-11-03 | — | — | EP | disclosed |