SCHEMBL25878367

SCHEMBL25878367

Cc1ccc(-c2ccc(C)c(C)c2C)c(O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.50
TP53 P04637 5/20 0.48
TDP1 Q9NUW8 2/20 0.48
ACHE P22303 1/20 0.42
LMNA P02545 3/20 0.42
CHRM1 P11229 1/20 0.42
SLC6A2 P23975 1/20 0.42
ADRA1A P35348 1/20 0.42
HTR2B P41595 1/20 0.42
ALOX15 P16050 4/20 0.40
HSD17B10 Q99714 3/20 0.40
ALDH1A1 P00352 3/20 0.40
HPGD P15428 3/20 0.39
NPSR1 Q6W5P4 2/20 0.39
MAPT P10636 2/20 0.39
ALOX12 P18054 2/20 0.39
KDM4E B2RXH2 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL340066 0.83 TRPA1 (0.68) TRPA1TP53TDP1ACHELMNA
SCHEMBL29819939 0.83 TRPA1 (0.68) TRPA1TP53TDP1ACHELMNA
SCHEMBL23967969 0.82 MAPT (0.42) TP53TDP1LMNAALDH1A1HPGD
SCHEMBL16852427 0.79 TRPA1 (0.48) TRPA1TP53TDP1ALOX15HSD17B10
SCHEMBL8375606 0.79 TP53 (0.50) TRPA1TP53TDP1LMNAALOX15
SCHEMBL5687593 0.79 CASP1 (0.63) TRPA1TDP1LMNAALOX15HSD17B10
SCHEMBL27572785 0.78 ATM (0.48) TRPA1TP53TDP1LMNAALOX15
SCHEMBL31673873 0.78 POLB (0.55) TRPA1ACHELMNAALOX15HSD17B10
SCHEMBL23854312 0.78 POLB (0.55) TRPA1ACHELMNAALOX15HSD17B10
SCHEMBL16378659 0.77 TDP1 (0.37) TP53TDP1LMNAHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134594-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed