Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC1 | P78348 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | F9 | P00740 | 2/20 | 0.31 |
| ▸ | RXRA | P19793 | 2/20 | 0.30 |
| ▸ | RXRB | P28702 | 2/20 | 0.30 |
| ▸ | KIF11 | P52732 | 2/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16383158 | 0.88 | ASIC1 (0.41) | ASIC1DHODHNPC1HTTRAB9A | |
| SCHEMBL14927016 | 0.79 | ASIC1 (0.42) | ASIC1DHODHASIC3ALDH1A1MAPT | |
| SCHEMBL14927095 | 0.78 | MAPT (0.43) | ASIC1DHODHNPSR1LMNANPC1 | |
| SCHEMBL14927099 | 0.76 | DHODH (0.39) | ASIC1DHODHNPSR1LMNAALDH1A1 | |
| SCHEMBL14927098 | 0.73 | ALDH1A1 (0.42) | ASIC1DHODHNPSR1LMNAALDH1A1 | |
| SCHEMBL14927018 | 0.72 | KIF11 (0.39) | ASIC1DHODHALDH1A1MAPTRXRA | |
| SCHEMBL14927101 | 0.71 | KIF11 (0.46) | NPC1RAB9AALDH1A1MAPTRXRA | |
| SCHEMBL14927013 | 0.69 | PLAU (0.49) | DHODHASIC3RAB9AALDH1A1MAPT | |
| SCHEMBL14927019 | 0.69 | CTSS (0.38) | ASIC1ALDH1A1MAPTRXRARXRB | |
| SCHEMBL14927100 | 0.69 | DHODH (0.35) | DHODHNPSR1LMNAF9CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933096-B2 | Antimicrobial agents | Rugers, The State University of New Jersey (US) | 2015-01-13 | — | — | US | disclosed |