SCHEMBL16379252

SCHEMBL16379252

CCC1OC(OCCCCC(N)=O)C(OC(=O)c2ccccc2)C(C)C1C

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LGALS9 O00182 1/20 0.36
LGALS1 P09382 1/20 0.36
LGALS3 P17931 1/20 0.36
LGALS7; LGALS7B P47929 1/20 0.36
PTPN1 P18031 8/20 0.35
TDP1 Q9NUW8 3/20 0.35
MAOB P27338 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
BCHE P06276 1/20 0.34
LMNA P02545 1/20 0.33
PTPN2 P17706 2/20 0.33
PTPN6 P29350 2/20 0.33
PTPN11 Q06124 2/20 0.33
NT5E P21589 1/20 0.32
LTB4R Q15722 1/20 0.32
PPARA Q07869 1/20 0.32
SELP P16109 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9604579 0.93 PPARA (0.40) LGALS9LGALS1LGALS3LGALS7; LGALS7BPTPN1
SCHEMBL15341350 0.92 LGALS9 (0.36) LGALS9LGALS1LGALS3LGALS7; LGALS7BPTPN1
SCHEMBL15341352 0.88 PTPN1 (0.38) LGALS9LGALS1LGALS3LGALS7; LGALS7BPTPN1
SCHEMBL19500442 0.86 LGALS8 (0.39) PTPN1TDP1L3MBTL1BCHEPTPN2
SCHEMBL15829805 0.83 LGALS9 (0.36) LGALS9LGALS1LGALS3LGALS7; LGALS7BPTPN1
SCHEMBL16489268 0.83 LGALS9 (0.44) LGALS9LGALS1LGALS3LGALS7; LGALS7BPTPN1
SCHEMBL17773533 0.83 LGALS9 (0.44) LGALS9LGALS1LGALS3LGALS7; LGALS7BPTPN1
SCHEMBL16559641 0.82 MEN1 (0.39) LGALS9LGALS1LGALS3LGALS7; LGALS7BPTPN1
SCHEMBL19473213 0.82 MEN1 (0.39) LGALS9LGALS1LGALS3LGALS7; LGALS7BPTPN1
SCHEMBL13298881 0.81 ALDH1A1 (0.38) LGALS9LGALS1LGALS3LGALS7; LGALS7BPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9370581-B2 Carbohydrate conjugates as delivery agents for oligonucleotides ALNYLAM PHARMACEUTICALS, INC. (US) 2016-06-21 US disclosed
US-20150011615-A1 Carbohydrate Conjugates as Delivery Agents for Oligonucleotides BANK OF AMERICA, N.A. 2015-01-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150011615-A1 Carbohydrate Conjugates as Delivery Agents for Oligonucleotides LPXN, ZYX, OSTC LGALS9 387/4885LGALS1 616/4885LGALS3 533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.