SCHEMBL1638748

SCHEMBL1638748

c1ccc(C2CCON2)cc1

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
PRCP P42785 1/20 0.38
TSHR P16473 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
SLC6A2 P23975 1/20 0.36
ADRA1A P35348 1/20 0.36
HTR2B P41595 1/20 0.36
SLC6A3 Q01959 1/20 0.36
NPC1 O15118 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18921517 1.00 SLC18A3 (0.39) SLC18A3SIGMAR1MEN1KMT2APRCP
SCHEMBL22232773 1.00 SLC18A3 (0.39) SLC18A3SIGMAR1MEN1KMT2APRCP
SCHEMBL31087320 0.88 NLRP3 (0.37) SLC18A3SIGMAR1MEN1KMT2APRCP
SCHEMBL24726482 0.84 SLC5A2 (0.37) SLC18A3SIGMAR1MEN1KMT2AHTR2B
SCHEMBL29729987 0.84 SLC5A2 (0.37) SLC18A3SIGMAR1MEN1KMT2AHTR2B
SCHEMBL30678295 0.84 SLC5A2 (0.37) SLC18A3SIGMAR1MEN1KMT2AHTR2B
SCHEMBL30678290 0.80 KCNH2 (0.51) MEN1KMT2ATSHRNPC1
SCHEMBL29729997 0.80 KCNH2 (0.51) MEN1KMT2ATSHRNPC1
SCHEMBL30064507 0.80 KCNH2 (0.51) MEN1KMT2ATSHRNPC1
SCHEMBL30678293 0.80 GRM5 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250368635-A1 HETEROARYL DERIVATIVE COMPOUND, AND USES THEREOF VORONOI, INC. (KR) 2025-12-04 US claimed
WO-2022245085-A1 HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF 보로노이바이오 주식회사 2022-11-24 WO claimed
US-12534457-B2 Heteroaryl derivative compounds, and uses thereof VORONOI INC. (KR) 2026-01-27 US disclosed
US-12528799-B2 Heteroaryl derivative compounds, and uses thereof VORONOI INC. (KR) 2026-01-20 US disclosed
US-20250368635-A1 HETEROARYL DERIVATIVE COMPOUND, AND USES THEREOF VORONOI, INC. (KR) 2025-12-04 US disclosed
EP-4430037-B1 ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF GENZYME CORP (US) 2025-10-29 EP disclosed
EP-4631507-A2 HETEROARYL DERIVATIVE, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE COMPONENT Voronoi Inc. (KR) 2025-10-15 EP disclosed
EP-4619403-A1 HETEROARYL DERIVATIVE COMPOUND, AND USES THEREOF Voronoi, Inc. (KR) 2025-09-24 EP disclosed
EP-3943491-B1 HETEROARYL DERIVATIVE, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE COMPONENT VORONOI INC (KR) 2025-06-18 EP disclosed
US-20250122186-A1 ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF GENZYME CORP (US) 2025-04-17 US disclosed
US-20250019373-A1 ARYL OR HETEROARYL DERIVATIVE, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF KINASE-RELATED DISEASES VORONOI INC. (KR) 2025-01-16 US disclosed
US-20040018724-A1 Plating method SHIPLEY COMPANY, L.L.C (US) 2004-01-29 US disclosed
EP-1353228-A1 Method for depositing a very thick photoresist layer on a substrate and metal plating method Shipley Co. L.L.C. (US) 2003-10-15 EP disclosed
US-5900346-A NEGATIVE-ACTING PHOTORESIST COMPOSITION; PHOTOACTIVATOR THAT IS AN ORGANIC CARBONYL CONTAINING COMPOUND; CROSSLINKER. SHIPLEY COMPANY, L.L.C. (US) 1999-05-04 US disclosed
US-5478690-A Alkali developable photosensitive resin composition comprising a binder having betaine side groups NIPPON PAINT CO., LTD. (JP) 1995-12-26 US disclosed
EP-0499447-A1 Alkali developable photosensitive resin composition Nippon Paint Co., Ltd. (JP) 1992-08-19 EP disclosed
EP-0490118-A1 Photoimagable solder mask and photosensitive composition SHIPLEY COMPANY INC. (US) 1992-06-17 EP disclosed
US-4877818-A PHOTORESISTS ROHM AND HAAS COMPANY (US) 1989-10-31 US disclosed
US-4592816-A Forming negative images on conductive surfaces ROHM AND HAAS COMPANY (US) 1986-06-03 US disclosed
EP-0176356-A2 Photosensitive polymer compositions, electrophoretic deposition processes using same, and the use of same in forming films on substrates ROHM AND HAAS COMPANY (US) 1986-04-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250368635-A1 HETEROARYL DERIVATIVE COMPOUND, AND USES THEREOF ERBB2, EGFR, ERBB3 SLC18A3 4510/4885SIGMAR1 2989/4885MEN1 3930/4885
US-20250122186-A1 ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF RIPK1, RIPK2, RIPK3 SLC18A3 4567/4885SIGMAR1 2075/4885MEN1 4437/4885
US-12528799-B2 Heteroaryl derivative compounds, and uses thereof ERBB2, EGFR, ERBB3 SLC18A3 4538/4885SIGMAR1 166/4885MEN1 3907/4885
US-12534457-B2 Heteroaryl derivative compounds, and uses thereof ERBB2, EGFR, ERBB3 SLC18A3 4367/4885SIGMAR1 287/4885MEN1 2781/4885
US-20250019373-A1 ARYL OR HETEROARYL DERIVATIVE, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF KINASE-RELATED DISEASES RIPK1, RIPK2, RIPK3 SLC18A3 4854/4885SIGMAR1 3575/4885MEN1 4471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.