Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 5/20 | 0.47 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
| ▸ | FURIN | P09958 | 2/20 | 0.32 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16596164 | 0.93 | FAP (0.47) | FAPMAP1LC3BFOLH1OPRK1SIRT2 | |
| SCHEMBL16590726 | 0.93 | FAP (0.47) | FAPMAP1LC3BFOLH1OPRK1SIRT2 | |
| SCHEMBL24477196 | 0.90 | FAP (0.42) | FAPMAP1LC3BOPRK1SIRT2SIRT1 | |
| SCHEMBL23347003 | 0.90 | FAP (0.42) | FAPMAP1LC3BOPRK1SIRT2SIRT1 | |
| SCHEMBL21659206 | 0.90 | FAP (0.42) | FAPMAP1LC3BOPRK1SIRT2SIRT1 | |
| SCHEMBL25094809 | 0.90 | FAP (0.42) | FAPMAP1LC3BOPRK1SIRT2SIRT1 | |
| SCHEMBL24649271 | 0.90 | FAP (0.42) | FAPMAP1LC3BOPRK1SIRT2SIRT1 | |
| SCHEMBL23350883 | 0.90 | FAP (0.42) | FAPMAP1LC3BOPRK1SIRT2SIRT1 | |
| SCHEMBL23347004 | 0.90 | FAP (0.42) | FAPMAP1LC3BOPRK1SIRT2SIRT1 | |
| SCHEMBL24648759 | 0.90 | FAP (0.42) | FAPMAP1LC3BOPRK1SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9517276-B2 | Compositions and methods for conjugating activatable antibodies | CYTOMX THERAPEUTICS, INC. (US) | 2016-12-13 | — | — | US | disclosed |
| US-9517276-B2 | Compositions and methods for conjugating activatable antibodies | CYTOMX THERAPEUTICS, INC. (US) | 2016-12-13 | — | — | US | disclosed |
| US-20150005477-A1 | COMPOSITIONS AND METHODS FOR CONJUGATING ACTIVATABLE ANTIBODIES | CYTOMX THERAPEUTICS, INC. | 2015-01-01 | — | — | US | disclosed |
| US-20150005477-A1 | COMPOSITIONS AND METHODS FOR CONJUGATING ACTIVATABLE ANTIBODIES | CYTOMX THERAPEUTICS, INC. | 2015-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150005477-A1 | COMPOSITIONS AND METHODS FOR CONJUGATING ACTIVATABLE ANTIBODIES | FCGR3B, FCGR2A, FCGR1A | FAP 1991/4885MAP1LC3B 1381/4885FOLH1 715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.