SCHEMBL1638787

SCHEMBL1638787

CO[Si](OC)(OC)c1ccc2ccccc2c1[Si](OC)(OC)OC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.41
ALDH1A1 P00352 5/20 0.41
CYP2A6 P11509 4/20 0.41
TSHR P16473 3/20 0.41
HSD17B10 Q99714 3/20 0.41
TDP1 Q9NUW8 1/20 0.41
POLB P06746 1/20 0.38
HPRT1 P00492 1/20 0.38
KDM4E B2RXH2 2/20 0.37
MAPK1 P28482 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CYP1A2 P05177 3/20 0.36
HIF1A Q16665 2/20 0.35
CYP1B1 Q16678 1/20 0.35
CYP3A4 P08684 2/20 0.33
HPGD P15428 2/20 0.33
CYP2C19 P33261 2/20 0.33
NISCH Q9Y2I1 1/20 0.33
CASP1 P29466 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28959324 0.91 HPRT1 (0.48) MAPTALDH1A1CYP2A6TSHRHSD17B10
SCHEMBL17373047 0.84 NQO1 (0.40) MAPTALDH1A1CYP2A6HSD17B10TDP1
SCHEMBL28351386 0.81 CYP2A6 (0.50) MAPTALDH1A1CYP2A6TSHRHSD17B10
SCHEMBL1640203 0.79 POLB (0.37) MAPTALDH1A1CYP2A6HSD17B10POLB
SCHEMBL6702610 0.79 ALDH1A1 (0.42) MAPTALDH1A1CYP2A6TSHRHSD17B10
SCHEMBL1974164 0.79 MAPT (0.58) MAPTALDH1A1POLBKDM4ESMN1; SMN2
SCHEMBL105580 0.78 ALDH1A1 (0.43) MAPTALDH1A1CYP2A6TSHRHSD17B10
SCHEMBL29417586 0.78 POLB (0.42) MAPTALDH1A1CYP2A6HSD17B10POLB
SCHEMBL29503122 0.78 ALDH1A1 (0.43) MAPTALDH1A1CYP2A6TSHRHSD17B10
SCHEMBL2346357 0.78 POLB (0.42) MAPTALDH1A1CYP2A6HSD17B10POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11592945-B2 Dielectric siloxane particle films and devices having the same INKRON OY (FI) 2023-02-28 US disclosed
CN-106605309-B LED lamp, manufacturing method of LED lamp and sealing method of LED device 英克伦股份有限公司 2022-10-18 CN disclosed
US-11289666-B2 Electrically conductive siloxane particle films, and devices with the same INKRON OY (FI) 2022-03-29 US disclosed
EP-3158595-B1 LED LAMP WITH SILOXANE PARTICLE MATERIAL INKRON OY (FI) 2021-12-01 EP disclosed
EP-3359991-B1 DISPLAYS COMPRISING DIELECTRIC SILOXANE POLYMER FILMS INKRON OY (FI) 2021-09-29 EP disclosed
US-11084928-B2 Transparent siloxane encapsulant and adhesive INKRON OY (FI) 2021-08-10 US disclosed
CN-109081921-B Silicon-based hard mask 罗门哈斯电子材料有限责任公司 2021-07-06 CN disclosed
US-11001674-B2 Method of making a siloxane polymer composition INKRON OY (FI) 2021-05-11 US disclosed
EP-3359373-B1 METHOD FOR MAKING A 3D PRINTED ARTICLE AND 3D PRINTED ARTICLE INKRON OY (FI) 2021-04-14 EP disclosed
US-10818493-B2 Silicon-based hardmask ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2020-10-27 US disclosed
WO-2015193557-A1 DIELECTRIC SILOXANE PARTICLE FILMS, AND DEVICES HAVING THE SAME INKRON OY (FI) 2015-12-23 WO disclosed
WO-2015193556-A1 COMPOSITION HAVING SILOXANE POLYMER AND PARTICLE INKRON OY (FI) 2015-12-23 WO disclosed
WO-2015193554-A1 TRANSPARENT SILOXANE ENCAPSULANT AND ADHESIVE INKRON OY (FI) 2015-12-23 WO disclosed
WO-2015193558-A1 A METHOD OF MAKING A SILOXANE POLYMER COMPOSITION INKRON OY (FI) 2015-12-23 WO disclosed
EP-1391476-B1 PHOTOREACTIVE COMPOSITION SEKISUI CHEMICAL CO LTD (JP) 2015-12-09 EP disclosed
US-8536242-B2 Photocurable composition SEKISUI CHEMICAL CO., LTD. (JP) 2013-09-17 US disclosed
US-20110097669-A1 PHOTOCURABLE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2011-04-28 US disclosed
US-7312013-B2 Photoreactive composition SEKISUI CHEMICAL CO., LTD. (JP) 2007-12-25 US disclosed
US-20040202956-A1 a photocurable mixture of a hydrolyzable metal (silyl) compound and a reaction, polymerization or crosslinking promoter; curing; adhesives, seals, semiconductors, dielectrics, microlenses, optical fibers, color filters, gas permeable films SEKISUI CHEMICAL CO., LTD. (JP) 2004-10-14 US disclosed
EP-1391476-A1 PHOTOREACTIVE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2004-02-25 EP disclosed