Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 11/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1680202 | 0.85 | RAB9A (0.59) | HSD17B10KDM4ETSHRSMN1; SMN2RAB9A | |
| SCHEMBL2423066 | 0.83 | NPC1 (0.49) | HSD17B10KDM4ESMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL27768803 | 0.83 | KDM4E (0.58) | HSD17B10KDM4ETSHRSMN1; SMN2RAB9A | |
| SCHEMBL12571309 | 0.82 | KDM4E (0.57) | HSD17B10KDM4ETSHRSMN1; SMN2RAB9A | |
| SCHEMBL12725592 | 0.81 | KDM4E (0.55) | HSD17B10KDM4ETSHRSMN1; SMN2RAB9A | |
| SCHEMBL12278020 | 0.80 | HSD17B10 (0.55) | HSD17B10KDM4ETSHRSMN1; SMN2RAB9A | |
| SCHEMBL2405896 | 0.80 | HSD17B10 (0.55) | HSD17B10KDM4ETSHRSMN1; SMN2RAB9A | |
| SCHEMBL18265428 | 0.80 | CYP1A2 (0.61) | HSD17B10KDM4ETSHRSMN1; SMN2RAB9A | |
| SCHEMBL18195379 | 0.80 | ALDH1A1 (0.54) | HSD17B10KDM4ETSHRSMN1; SMN2RAB9A | |
| SCHEMBL1423771 | 0.79 | KDM4E (0.54) | HSD17B10KDM4ETSHRSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2730569-B1 | New amides and thioamides as pest control agents | BAYER CROPSCIENCE AG (DE) | 2016-11-30 | — | — | EP | disclosed |
| US-20160316755-A1 | Novel Heteroaromatic Amides and Thioamides as Pesticides | BAYER CROPSCIENCE AG (DE) | 2016-11-03 | — | — | US | disclosed |
| US-20160316755-A1 | Novel Heteroaromatic Amides and Thioamides as Pesticides | BAYER CROPSCIENCE AG (DE) | 2016-11-03 | — | — | US | disclosed |
| US-20160316755-A1 | Novel Heteroaromatic Amides and Thioamides as Pesticides | BAYER CROPSCIENCE AG (DE) | 2016-11-03 | — | — | US | disclosed |
| US-9428487-B2 | Heteroaromatic amides and thioamides as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-08-30 | — | — | US | disclosed |
| US-9428487-B2 | Heteroaromatic amides and thioamides as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-08-30 | — | — | US | disclosed |
| US-9428487-B2 | Heteroaromatic amides and thioamides as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-08-30 | — | — | US | disclosed |
| EP-2730569-A1 | New amides and thioamides as pest control agents | Bayer CropScience AG (DE) | 2014-05-14 | — | — | EP | disclosed |
| EP-2730568-A1 | NEW HETEROAROMATIC AMIDES AND THIOAMIDES AS PEST CONTROL AGENTS | Bayer CropScience AG (DE) | 2014-05-14 | — | — | EP | disclosed |
| EP-2725023-A1 | New heteroaromatic amides as pest control agents | Bayer CropScience AG (DE) | 2014-04-30 | — | — | EP | disclosed |
| EP-2725020-A1 | New heteroaromatic amides and thioamides as pest control agents | Bayer CropScience AG (DE) | 2014-04-30 | — | — | EP | disclosed |
| US-20110098287-A1 | Novel Heteroaromatic Amides And Thioamides As Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-04-28 | — | — | US | disclosed |
| US-20110098287-A1 | Novel Heteroaromatic Amides And Thioamides As Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-04-28 | — | — | US | disclosed |
| US-20110098287-A1 | Novel Heteroaromatic Amides And Thioamides As Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-04-28 | — | — | US | disclosed |
| WO-2009149858-A1 | NOVEL HETEROAROMATIC AMIDES AND THIOAMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2009-12-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160316755-A1 | Novel Heteroaromatic Amides and Thioamides as Pesticides | AADAC, DDT, TST | HSD17B10 2938/4885KDM4E 2366/4885TSHR 138/4885 |
| US-20110098287-A1 | Novel Heteroaromatic Amides And Thioamides As Pesticides | AADAC, DDT, TST | HSD17B10 2938/4885KDM4E 2366/4885TSHR 138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.