Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12571309 | 0.89 | KDM4E (0.57) | KDM4ESMN1; SMN2HSD17B10RAB9AALDH1A1 | |
| SCHEMBL1680202 | 0.89 | RAB9A (0.59) | KDM4ESMN1; SMN2HSD17B10RAB9AALDH1A1 | |
| SCHEMBL12725592 | 0.87 | KDM4E (0.55) | KDM4ESMN1; SMN2HSD17B10RAB9AALDH1A1 | |
| SCHEMBL1423771 | 0.86 | KDM4E (0.54) | KDM4ESMN1; SMN2HSD17B10RAB9AALDH1A1 | |
| SCHEMBL1638860 | 0.83 | HSD17B10 (0.61) | KDM4ESMN1; SMN2HSD17B10RAB9AALDH1A1 | |
| SCHEMBL18265428 | 0.83 | CYP1A2 (0.61) | KDM4ESMN1; SMN2HSD17B10RAB9AALDH1A1 | |
| SCHEMBL18195379 | 0.83 | ALDH1A1 (0.54) | KDM4ESMN1; SMN2HSD17B10RAB9AALDH1A1 | |
| SCHEMBL1424931 | 0.82 | KDM4E (0.75) | KDM4ESMN1; SMN2HSD17B10RAB9AALDH1A1 | |
| SCHEMBL27768576 | 0.80 | NPC1 (0.51) | KDM4ESMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL1638585 | 0.80 | CDC7 (0.56) | KDM4ESMN1; SMN2HSD17B10RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |