SCHEMBL16389934

SCHEMBL16389934

CCCCCCCC/C=C/CCCCCCCCNC(CCN)CCCN

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC6A5 Q9Y345 3/20 0.48
PPARA Q07869 2/20 0.44
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
RRM1 P23921 1/20 0.39
FAAH O00519 2/20 0.38
TRPV1 Q8NER1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16389935 1.00 SLC6A5 (0.48) SLC6A5PPARAKDM4EALDH1A1RRM1
SCHEMBL31284016 0.91 KDM4E (0.43) SLC6A5PPARAKDM4E
SCHEMBL20142348 0.90 RRM1 (0.45) ALDH1A1RRM1
SCHEMBL28205624 0.90 RRM1 (0.45) ALDH1A1RRM1
SCHEMBL10917345 0.89 SLC6A5 (0.46) SLC6A5PPARAKDM4EALDH1A1RRM1
Hydrochloric Acid SCHEMBL10591072 0.85 KDM4E (0.47) SLC6A5PPARAKDM4EALDH1A1FAAH
SCHEMBL31090424 0.85 GNAI3 (0.47) ALDH1A1RRM1
SCHEMBL31090421 0.85 RRM1 (0.46) ALDH1A1RRM1
SCHEMBL1961323 0.84 SLC6A5 (0.42) SLC6A5PPARAKDM4EALDH1A1FAAH
SCHEMBL22205254 0.83 DNM1 (0.44) ALDH1A1RRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2826843-B1 Amide alcohol friction modifiers for lubricating oils AFTON CHEMICAL CORP (US) 2017-05-10 EP disclosed
US-9193932-B2 Amide alcohol friction modifiers for lubricating oils AFTON CHEMICAL CORPORATION (US) 2015-11-24 US disclosed
US-20150024986-A1 AMIDE ALCOHOL FRICTION MODIFIERS FOR LUBRICATING OILS AFTON CHEMICAL CORPORATION 2015-01-22 US disclosed
EP-2826843-A1 Amide alcohol friction modifiers for lubricating oils Afton Chemical Corporation (US) 2015-01-21 EP disclosed