Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5177256 | 0.84 | PTPN1 (0.39) | ALDH1A1KDM4EPTPRCLMNA | |
| SCHEMBL16390865 | 0.84 | MAPT (0.44) | ALDH1A1KDM4ELMNA | |
| SCHEMBL21612913 | 0.83 | ALDH1A1 (0.34) | TDP1ALDH1A1KDM4EPTPRCLMNA | |
| SCHEMBL21612893 | 0.82 | ALDH1A1 (0.35) | TDP1ALDH1A1KDM4ELMNA | |
| SCHEMBL17048204 | 0.81 | CYP4F2 (0.47) | L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL16390958 | 0.79 | HDAC8 (0.37) | HDAC8L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL16390799 | 0.79 | PPARA (0.44) | HDAC8ALDH1A1LMNA | |
| SCHEMBL29068363 | 0.78 | CA12 (0.50) | L3MBTL1TDP1 | |
| SCHEMBL2200101 | 0.78 | CA12 (0.53) | TDP1 | |
| SCHEMBL16673260 | 0.77 | L3MBTL1 (0.52) | L3MBTL1TDP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155194-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2015-01-21 | — | — | EP | disclosed |