Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21612913 | 0.99 | ALDH1A1 (0.34) | ALDH1A1KDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL5177256 | 0.86 | PTPN1 (0.39) | ALDH1A1KDM4ELMNAKMT2APTPN1 | |
| SCHEMBL16390959 | 0.82 | HDAC8 (0.36) | ALDH1A1KDM4ELMNATDP1 | |
| SCHEMBL3793478 | 0.80 | KDM4E (0.37) | ALDH1A1KDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL18858804 | 0.79 | PKM (0.46) | ALDH1A1KDM4EPTPN1MAPTPOLB | |
| SCHEMBL29068363 | 0.75 | CA12 (0.50) | TDP1CYP2C19BCHECNR2 | |
| SCHEMBL25182441 | 0.74 | APLNR (0.35) | ALDH1A1KDM4ESMN1; SMN2TDP1POLB | |
| SCHEMBL20535201 | 0.74 | APLNR (0.35) | ALDH1A1KDM4ESMN1; SMN2TDP1POLB | |
| SCHEMBL20535616 | 0.74 | APLNR (0.35) | ALDH1A1KDM4ESMN1; SMN2TDP1POLB | |
| SCHEMBL20535618 | 0.74 | APLNR (0.35) | ALDH1A1KDM4ESMN1; SMN2TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020009176-A1 | AMIDE COMPOUND HAVING BET PROTEOLYSIS-INDUCING ACTION AND MEDICINAL APPLICATION THEREOF | 田辺三菱製薬株式会社 | 2020-01-09 | — | — | WO | disclosed |