Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 2/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | GPR68 | Q15743 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1640993 | 0.87 | HSD17B1 (0.31) | — | |
| SCHEMBL28024657 | 0.87 | — | — | |
| SCHEMBL27883625 | 0.85 | — | — | |
| SCHEMBL28008851 | 0.84 | — | — | |
| SCHEMBL18917419 | 0.84 | MAOA (0.34) | — | |
| SCHEMBL18917439 | 0.83 | KMO (0.37) | — | |
| SCHEMBL28188074 | 0.83 | — | — | |
| SCHEMBL28311234 | 0.82 | MMP3 (0.33) | — | |
| SCHEMBL28121970 | 0.82 | MAOA (0.33) | — | |
| SCHEMBL28164514 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493897-A1 | HYDROXY-SUBSTITUTED GOLD(III) PORPHYRIN COMPLEXES AS HISTONE DEACETYLASE INHIBITORS | The University of Hong Kong (CN) | 2012-09-05 | — | — | EP | claimed |
| WO-2011050575-A1 | HYDROXY-SUBSTITUTED GOLD(III) PORPHYRIN COMPLEXES AS HISTONE DEACETYLASE INHIBITORS | THE UNIVERSITY OF HONG KONG (CN) | 2011-05-05 | — | — | WO | claimed |
| US-20110098263-A1 | HYDROXY-SUBSTITUTED COLD(III) PORPHYRIN COMPLEXES AS HISTONE DEACETYLASE INHIBITORS | CHE CHI MING | 2011-04-28 | — | — | US | claimed |
| US-8563712-B2 | Hydroxy-substituted gold(III) porphyrin complexes as histone deacetylase inhibitors | THE UNIVERSITY OF HONG KONG (HK) | 2013-10-22 | — | — | US | disclosed |
| EP-2493897-A1 | HYDROXY-SUBSTITUTED GOLD(III) PORPHYRIN COMPLEXES AS HISTONE DEACETYLASE INHIBITORS | The University of Hong Kong (CN) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011050575-A1 | HYDROXY-SUBSTITUTED GOLD(III) PORPHYRIN COMPLEXES AS HISTONE DEACETYLASE INHIBITORS | THE UNIVERSITY OF HONG KONG (CN) | 2011-05-05 | — | — | WO | disclosed |
| US-20110098263-A1 | HYDROXY-SUBSTITUTED COLD(III) PORPHYRIN COMPLEXES AS HISTONE DEACETYLASE INHIBITORS | CHE CHI MING | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098263-A1 | HYDROXY-SUBSTITUTED COLD(III) PORPHYRIN COMPLEXES AS HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC8, HDAC3 | PRKCI 2326/4885FYN 4497/4885HTR1A 4640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.