Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.55 |
| ▸ | ERN1 | O75460 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | BRD4 | O60885 | 4/20 | 0.54 |
| ▸ | LIPE | Q05469 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26013299 | 0.90 | MAPT (0.63) | HTR1AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL30416387 | 0.86 | HTR1A (0.74) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL791853 | 0.86 | HTR1A (0.74) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| Ammonia Solution, Strong SCHEMBL2063054 | 0.84 | HTR1A (0.72) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL5109238 | 0.81 | PTGER1 (0.66) | HTR1AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL1638070 | 0.81 | BCHE (0.50) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL201074 | 0.80 | RXRA (0.70) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL2574242 | 0.80 | MAPT (0.48) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL5096276 | 0.79 | HTR1A (0.53) | HTR1AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL1253794 | 0.79 | MAPT (0.85) | HTR1AADRA1DADRA1AADRA1BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8541521-B2 | Catalyst compounds and use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-09-24 | — | — | US | disclosed |
| EP-2493933-A2 | CATALYST COMPOUNDS AND USE THEREOF | ExxonMobil Chemical Patents Inc. (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011056424-A2 | CATALYST COMPOUNDS AND USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-05-12 | — | — | WO | disclosed |
| US-20110098427-A1 | Catalyst Compounds And Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098427-A1 | Catalyst Compounds And Use Thereof | THEM6, OPRM1, NOTUM | HTR1A 3549/4885ADRA1D 4308/4885ADRA1A 3978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.