Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 3/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | BAD | Q92934 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5805562 | 0.82 | MCL1 (0.47) | MCL1LIMK1EDNRALMNAMAPK1 | |
| SCHEMBL16396113 | 0.80 | LIMK1 (0.68) | ACLYMCL1LIMK1LMNAMAPK1 | |
| SCHEMBL2748545 | 0.72 | HSD17B2 (0.53) | ACLYMCL1HSD17B2 | |
| SCHEMBL15697522 | 0.72 | MCL1 (0.54) | MCL1LIMK1EDNRALMNAMAPK1 | |
| SCHEMBL18088617 | 0.71 | KEAP1 (0.42) | ACLYLIMK1 | |
| SCHEMBL27419975 | 0.71 | KDM4E (0.48) | LIMK1 | |
| SCHEMBL5808504 | 0.69 | LMNA (0.58) | LIMK1LMNAMAPK1 | |
| SCHEMBL17973603 | 0.69 | MCL1 (0.50) | MCL1LIMK1LMNAMAPK1PRNP | |
| SCHEMBL2958622 | 0.68 | MCL1 (0.61) | MCL1LIMK1EDNRALMNAMAPK1 | |
| SCHEMBL28600336 | 0.68 | MCL1 (0.49) | MCL1LIMK1LMNAMAPK1PRNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006101454-A1 | BENZOTHIOPHENE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*BIO PTE LTD (SG) | 2006-09-28 | — | — | WO | claimed |