Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6938990 | 0.85 | GFER (0.61) | KMT2AMEN1GAAPOLBGFER | |
| SCHEMBL6938287 | 0.85 | GFER (0.54) | KMT2AMEN1GAAGFERALDH1A1 | |
| SCHEMBL15442934 | 0.82 | ALDH1A1 (0.51) | KMT2AMEN1GAAESR1ESR2 | |
| SCHEMBL10492006 | 0.81 | KMT2A (0.60) | KMT2AMEN1GAAESR1ESR2 | |
| SCHEMBL9231994 | 0.78 | MEN1 (0.68) | KMT2AMEN1GAAESR1ESR2 | |
| SCHEMBL26326698 | 0.78 | L3MBTL1 (0.71) | KMT2AMEN1GAAALDH1A1MAPT | |
| SCHEMBL9054847 | 0.78 | HTT (0.54) | KMT2AMEN1GAAESR1ESR2 | |
| SCHEMBL21436956 | 0.78 | ALDH1A1 (0.45) | KMT2AMEN1GAAGFERALDH1A1 | |
| SCHEMBL10413156 | 0.77 | HTT (0.60) | KMT2AMEN1GAAALDH1A1MAPT | |
| SCHEMBL6938753 | 0.77 | HTT (0.60) | KMT2AMEN1GAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110097269-A1 | PHENYLOXYANILINE DERIVATIVES | LEHMANN LUTZ | 2011-04-28 | — | — | US | disclosed |
| US-7803960-B2 | Phenyloxyaniline derivatives | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-09-28 | — | — | US | disclosed |
| US-20080177108-A1 | Phenyloxyaniline derivatives | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110097269-A1 | PHENYLOXYANILINE DERIVATIVES | PNMT, PAH, NAT1 | KMT2A 1024/4885MEN1 4239/4885GAA 288/4885 |
| US-20080177108-A1 | Phenyloxyaniline derivatives | PNMT, PAH, NAT1 | KMT2A 1024/4885MEN1 4239/4885GAA 288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.