SCHEMBL26326698

SCHEMBL26326698

COc1ccc2cc(OS(=O)(=O)c3ccc(C)cc3)ccc2c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.71
TDP1 Q9NUW8 2/20 0.71
HTT P42858 2/20 0.71
LMNA P02545 1/20 0.71
SMN1; SMN2 Q16637 1/20 0.71
MEN1 O00255 2/20 0.68
KMT2A Q03164 2/20 0.68
GAA P10253 1/20 0.54
MAPK1 P28482 1/20 0.54
MAOB P27338 1/20 0.51
CA12 O43570 2/20 0.50
CA2 P00918 2/20 0.50
TUBB4A P04350 1/20 0.50
TUBB P07437 1/20 0.50
TUBA3C P0DPH7 1/20 0.50
TUBA1B P68363 1/20 0.50
TUBA4A P68366 1/20 0.50
TUBB4B P68371 1/20 0.50
TUBB3 Q13509 1/20 0.50
TUBB2A Q13885 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12204960 0.92 TDP1 (0.74) L3MBTL1TDP1HTTLMNASMN1; SMN2
SCHEMBL8794066 0.90 MEN1 (0.82) L3MBTL1TDP1HTTLMNASMN1; SMN2
SCHEMBL6938467 0.87 LMNA (0.58) L3MBTL1TDP1HTTLMNASMN1; SMN2
SCHEMBL29870275 0.87 L3MBTL1 (0.77) L3MBTL1TDP1HTTLMNASMN1; SMN2
SCHEMBL6882887 0.87 L3MBTL1 (0.77) L3MBTL1TDP1HTTLMNASMN1; SMN2
SCHEMBL6938753 0.86 HTT (0.60) L3MBTL1TDP1HTTLMNASMN1; SMN2
SCHEMBL10413156 0.86 HTT (0.60) L3MBTL1TDP1HTTLMNASMN1; SMN2
SCHEMBL2066126 0.85 MEN1 (0.67) L3MBTL1TDP1HTTLMNASMN1; SMN2
SCHEMBL13924688 0.85 MEN1 (0.67) L3MBTL1TDP1HTTLMNASMN1; SMN2
Iodide SCHEMBL9733834 0.84 HTT (0.58) L3MBTL1TDP1HTTLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230271988-A1 METHOD FOR PRODUCING ORGANOMETALLIC NUCLEOPHILE AND REACTION METHOD USING ORGANOMETALLIC NUCLEOPHILE NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2023-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230271988-A1 METHOD FOR PRODUCING ORGANOMETALLIC NUCLEOPHILE AND REACTION METHOD USING ORGANOMETALLIC NUCLEOPHILE HPD, TALDO1, OGG1 L3MBTL1 2878/4885TDP1 2696/4885HTT 3473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.