Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.72 |
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16398970 | 0.87 | ALOX5 (0.92) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL16398631 | 0.85 | MEN1 (0.72) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL16399225 | 0.85 | MAPT (0.72) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL31614562 | 0.85 | KMT2A (0.72) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL6202919 | 0.82 | MEN1 (0.61) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL8674798 | 0.81 | KMT2A (0.65) | KMT2AMAPTMEN1ALDH1A1RAB9A | |
| SCHEMBL1982760 | 0.81 | GSK3B (0.66) | KMT2AMAPTMEN1ALDH1A1RAB9A | |
| SCHEMBL16397992 | 0.81 | ALOX5 (0.68) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL16398364 | 0.80 | RAB9A (1.00) | KMT2AMAPTKDM4EALDH1A1ALOX5 | |
| SCHEMBL15706788 | 0.80 | RAB9A (0.76) | KMT2AMAPTMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834570-B2 | One step process for regioselective synthesis of α-acyloxy carbonyls | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-12-05 | — | — | US | claimed |
| US-20160115182-A1 | ONE STEP PROCESS FOR REGIOSELECTIVE SYNTHESIS OF ALPHA-ACYLOXY CARBONYLS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-04-28 | — | — | US | claimed |
| WO-2014195972-A1 | ONE STEP PROCESS FOR REGIOSELECTIVE SYNTHESIS OF α-ACYLOXY CARBONYLS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2014-12-11 | — | — | WO | claimed |
| US-9834570-B2 | One step process for regioselective synthesis of α-acyloxy carbonyls | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-12-05 | — | — | US | disclosed |
| US-9834570-B2 | One step process for regioselective synthesis of α-acyloxy carbonyls | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-12-05 | — | — | US | disclosed |
| US-20160115182-A1 | ONE STEP PROCESS FOR REGIOSELECTIVE SYNTHESIS OF ALPHA-ACYLOXY CARBONYLS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-04-28 | — | — | US | disclosed |
| US-20160115182-A1 | ONE STEP PROCESS FOR REGIOSELECTIVE SYNTHESIS OF ALPHA-ACYLOXY CARBONYLS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-04-28 | — | — | US | disclosed |
| WO-2014195972-A1 | ONE STEP PROCESS FOR REGIOSELECTIVE SYNTHESIS OF α-ACYLOXY CARBONYLS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2014-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160115182-A1 | ONE STEP PROCESS FOR REGIOSELECTIVE SYNTHESIS OF ALPHA-ACYLOXY CARBONYLS | ACACB, ACACA, COASY | KMT2A 1405/4885MAPT 3521/4885MEN1 1721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.