SCHEMBL16399142

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18005195	0.90	RAB9A (0.49)	KDM4ERAB9ASMN1; SMN2LMNAMAPT
	SCHEMBL18005024	0.88	CDC25A (0.55)	KDM4ERAB9ASMN1; SMN2LMNAMAPT
	SCHEMBL18005017	0.87	CYP1A1 (0.35)	KDM4ERAB9ASMN1; SMN2LMNAMAPT
	SCHEMBL18005019	0.87	RAB9A (0.49)	KDM4ERAB9ASMN1; SMN2LMNAMAPT
	SCHEMBL18005984	0.87	RAB9A (0.46)	KDM4ERAB9ASMN1; SMN2LMNAMAPT
	SCHEMBL18005014	0.87	KDM4E (0.49)	KDM4ERAB9ALMNAMAPTMEN1
	SCHEMBL18005982	0.87	KMT2A (0.47)	KDM4ERAB9ASMN1; SMN2LMNAMAPT
	SCHEMBL16399594	0.86	EIF4E (0.48)	KDM4ERAB9AMEN1KMT2ANPC1
	SCHEMBL16399551	0.86	EIF4E (0.39)	—
	SCHEMBL18005018	0.85	CYP19A1 (0.46)	LMNAMAPTCYP19A1ADORA1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.