SCHEMBL16399166

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16399110	0.89	SRD5A2 (0.53)	SRD5A2SRD5A1CYP26A1NPC1RAB9A
	SCHEMBL18002464	0.88	SRD5A2 (0.50)	SRD5A2SRD5A1CYP26A1NPC1RAB9A
	SCHEMBL18002186	0.88	SRD5A2 (0.50)	SRD5A2SRD5A1CYP26A1NPC1RAB9A
	SCHEMBL18002674	0.86	SRD5A2 (0.48)	SRD5A2SRD5A1CYP26A1NPC1RAB9A
	SCHEMBL18002335	0.85	SRD5A2 (0.50)	SRD5A2SRD5A1CYP26A1NPC1RAB9A
	SCHEMBL18002604	0.85	SRD5A2 (0.50)	SRD5A2SRD5A1CYP26A1TDP1ALDH1A1
	SCHEMBL18003025	0.85	SRD5A2 (0.47)	SRD5A2SRD5A1CYP26A1ALDH1A1POLB
	SCHEMBL18002526	0.84	SRD5A2 (0.47)	SRD5A2SRD5A1CYP26A1FFAR1
	SCHEMBL12577906	0.83	SRD5A2 (0.62)	SRD5A2SRD5A1RAB9AALDH1A1KDM4E
	SCHEMBL16398920	0.82	NPC1 (0.52)	SRD5A2SRD5A1TDP1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.