Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18003240 | 0.90 | SLC6A4 (0.45) | SRD5A2SRD5A1L3MBTL1TDP1AHR | |
| SCHEMBL16399110 | 0.89 | SRD5A2 (0.53) | SRD5A2SRD5A1L3MBTL1POLBALDH1A1 | |
| SCHEMBL18003237 | 0.85 | IDO1 (0.47) | L3MBTL1TDP1AHRPOLBALDH1A1 | |
| SCHEMBL18002415 | 0.85 | SRD5A2 (0.42) | SRD5A2SRD5A1L3MBTL1TDP1POLB | |
| SCHEMBL18002464 | 0.85 | SRD5A2 (0.50) | SRD5A2SRD5A1L3MBTL1POLBALDH1A1 | |
| SCHEMBL18002186 | 0.85 | SRD5A2 (0.50) | SRD5A2SRD5A1L3MBTL1POLBALDH1A1 | |
| SCHEMBL16399166 | 0.85 | SRD5A2 (0.50) | SRD5A2SRD5A1L3MBTL1TDP1POLB | |
| SCHEMBL18002335 | 0.85 | SRD5A2 (0.50) | SRD5A2SRD5A1L3MBTL1POLBALDH1A1 | |
| SCHEMBL18002674 | 0.83 | SRD5A2 (0.48) | SRD5A2SRD5A1L3MBTL1POLBALDH1A1 | |
| SCHEMBL12577906 | 0.83 | SRD5A2 (0.62) | SRD5A2SRD5A1L3MBTL1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |
| US-10626095-B2 | Cyanotriazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-04-21 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | CS, PC, ACAT1 | SRD5A2 937/4885SRD5A1 764/4885L3MBTL1 1503/4885 |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | CS, PC, ACAT1 | SRD5A2 937/4885SRD5A1 764/4885L3MBTL1 1503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.