Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 10/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | F9 | P00740 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18004043 | 0.92 | IDO1 (0.41) | NR1H2MRGPRX4NR1H3CYP11B1CYP11B2 | |
| SCHEMBL16399337 | 0.91 | NR1H2 (0.38) | NR1H2MRGPRX4NR1H3CYP11B1CYP11B2 | |
| SCHEMBL18004427 | 0.87 | SCN1A (0.40) | NR1H2MRGPRX4NR1H3CYP11B1CYP11B2 | |
| SCHEMBL26071038 | 0.86 | NR1H2 (0.41) | NR1H2MRGPRX4NR1H3F9F10 | |
| SCHEMBL18004408 | 0.85 | KDM4A (0.41) | NR1H2MRGPRX4NR1H3CYP11B1CYP11B2 | |
| SCHEMBL18003993 | 0.84 | NR4A2 (0.50) | NR1H2MRGPRX4NR1H3MAPT | |
| SCHEMBL18005970 | 0.83 | NR4A2 (0.46) | CYP11B1CYP11B2F9F10KDM4E | |
| SCHEMBL18004436 | 0.83 | NR4A2 (0.41) | NR1H2MRGPRX4NR1H3CYP11B1KDM4E | |
| SCHEMBL18004039 | 0.82 | NR1H2 (0.42) | NR1H2MRGPRX4NR1H3CYP11B1CYP11B2 | |
| SCHEMBL18004433 | 0.82 | NR4A2 (0.47) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-04-21 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | CS, PC, ACAT1 | NR1H2 552/4885MRGPRX4 4062/4885NR1H3 498/4885 |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | CS, PC, ACAT1 | NR1H2 552/4885MRGPRX4 4062/4885NR1H3 498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.