SCHEMBL16399488

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16399489	1.00	NFE2L2 (0.39)	NFE2L2PTGS1PTGS2ALOX5NQO2
	SCHEMBL18004386	0.88	HPGD (0.36)	PTGS1PTGS2ALOX5MAPTKDM4E
	SCHEMBL16399529	0.86	AHR (0.36)	NFE2L2PTGS1PTGS2ALOX5NQO2
	SCHEMBL16399531	0.86	AHR (0.36)	NFE2L2PTGS1PTGS2ALOX5NQO2
	SCHEMBL18004503	0.85	NQO2 (0.52)	NFE2L2PTGS1PTGS2ALOX5NQO2
	SCHEMBL18004540	0.85	ERBB2 (0.42)	NFE2L2ALOX5TP53MAPTGAA
	SCHEMBL18004470	0.84	PTGS1 (0.33)	NFE2L2PTGS1PTGS2NQO2TP53
	SCHEMBL16399657	0.83	NFE2L2 (0.44)	NFE2L2
	SCHEMBL17969068	0.83	NFE2L2 (0.44)	NFE2L2
	SCHEMBL18004508	0.82	NOTUM (0.35)	NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.