Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31432497 | 0.82 | MAPT (0.53) | CA12CA1CA9KDM4ERAB9A | |
| SCHEMBL31432580 | 0.82 | MAPT (0.47) | CA12CA1CA9KDM4ERAB9A | |
| SCHEMBL38654208 | 0.82 | MAPT (0.53) | CA12CA1CA9KDM4ERAB9A | |
| SCHEMBL1638024 | 0.82 | KDM4E (0.49) | KDM4ERAB9APOLBALDH1A1TUBB1 | |
| SCHEMBL26987755 | 0.81 | ALDH1A1 (0.58) | CA12CA1CA9KDM4EMEN1 | |
| SCHEMBL29675123 | 0.81 | FDPS (0.66) | MEN1POLBKMT2AALDH1A1HPGD | |
| SCHEMBL5638579 | 0.80 | CA12 (0.57) | CA12CA1CA9ALDH1A1HPGD | |
| SCHEMBL11815908 | 0.79 | L3MBTL1 (0.58) | CA12CA1CA9KDM4ERAB9A | |
| SCHEMBL3071450 | 0.78 | CA12 (0.56) | CA12CA1CA9POLBALDH1A1 | |
| SCHEMBL31432486 | 0.78 | ALDH1A1 (0.42) | CA12CA1CA9KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110097269-A1 | PHENYLOXYANILINE DERIVATIVES | LEHMANN LUTZ | 2011-04-28 | — | — | US | disclosed |
| US-7803960-B2 | Phenyloxyaniline derivatives | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-09-28 | — | — | US | disclosed |
| EP-2064176-A1 | PHENYLOXYANILINE DERIVATIVES | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-06-03 | — | — | EP | disclosed |
| US-20080177108-A1 | Phenyloxyaniline derivatives | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-07-24 | — | — | US | disclosed |
| US-20080177108-A1 | Phenyloxyaniline derivatives | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-07-24 | — | — | US | disclosed |
| US-20080177108-A1 | Phenyloxyaniline derivatives | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-07-24 | — | — | US | disclosed |
| WO-2008028533-A1 | PHENYLOXYANILINE DERIVATIVES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | disclosed |
| EP-1894915-A1 | Phenyloxyaniline derivatives | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-03-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110097269-A1 | PHENYLOXYANILINE DERIVATIVES | PNMT, PAH, NAT1 | CA12 3642/4885CA1 3152/4885CA9 2431/4885 |
| US-20080177108-A1 | Phenyloxyaniline derivatives | PNMT, PAH, NAT1 | CA12 3642/4885CA1 3152/4885CA9 2431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.