Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDF3 | Q7Z739 | 2/20 | 0.44 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.44 |
| ▸ | YTHDF1 | Q9BYJ9 | 2/20 | 0.44 |
| ▸ | YTHDF2 | Q9Y5A9 | 2/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | PDE9A | O76083 | 1/20 | 0.38 |
| ▸ | PDE1A | P54750 | 1/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16401598 | 0.81 | HCAR2 (0.43) | HCAR2DAOTAAR1IDO1AGXT | |
| SCHEMBL16401870 | 0.81 | HTR1B (0.43) | TAAR1CYP3A4 | |
| SCHEMBL16401452 | 0.80 | CALM1 (0.41) | HCAR2DAOTAAR1 | |
| SCHEMBL16401705 | 0.78 | HTR2C (0.44) | DAOTAAR1CYP3A4IDO1MPO | |
| SCHEMBL16401473 | 0.75 | CYP2D6 (0.43) | TAAR1MPO | |
| SCHEMBL3300276 | 0.71 | PNMT (0.65) | PNMTDAOTAAR1SIGMAR1CYP3A4 | |
| SCHEMBL2308097 | 0.69 | PNMT (0.44) | YTHDF3YTHDC1YTHDF1YTHDF2HCAR2 | |
| SCHEMBL28055734 | 0.69 | IDO1 (0.44) | YTHDF3YTHDC1YTHDF1YTHDF2HCAR2 | |
| SCHEMBL16401670 | 0.68 | KCNH2 (0.38) | DAOTAAR1CYP3A4 | |
| SCHEMBL16401969 | 0.67 | HRH3 (0.43) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007613-A1 | O-ALKYL TRIAZOLYL CARBAMATES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-01-22 | — | — | WO | disclosed |