Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16401452 | 0.80 | CALM1 (0.41) | CYP2D6TAAR1CYP1A2 | |
| SCHEMBL16401423 | 0.75 | YTHDF3 (0.44) | TAAR1MPO | |
| SCHEMBL1247974 | 0.72 | CYP2D6 (0.46) | CYP2D6NFKB1TAAR1CYP1A2CYP2A6 | |
| SCHEMBL16401705 | 0.72 | HTR2C (0.44) | CYP2D6TAAR1CYP1A2MPOHTR2A | |
| SCHEMBL2838141 | 0.71 | CYP1A2 (0.65) | CYP2D6NFKB1TAAR1CYP1A2CYP2A6 | |
| SCHEMBL16401670 | 0.68 | KCNH2 (0.38) | TAAR1CYP1A2CYP2A6HTR2A | |
| SCHEMBL28846677 | 0.67 | CYP1A2 (0.60) | CYP2D6NFKB1TAAR1CYP1A2CYP2A6 | |
| SCHEMBL5900962 | 0.67 | CYP1A2 (0.60) | CYP2D6NFKB1TAAR1CYP1A2CYP2A6 | |
| SCHEMBL8668107 | 0.66 | CYP2D6 (0.38) | CYP2D6NFKB1TAAR1CYP1A2CYP2A6 | |
| SCHEMBL18621239 | 0.66 | MPO (0.60) | CYP2D6NFKB1TAAR1ALOX5MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007613-A1 | O-ALKYL TRIAZOLYL CARBAMATES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-01-22 | — | — | WO | disclosed |