Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL913935 | 0.80 | BRD4 (0.33) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL15157189 | 0.75 | BRD4 (0.42) | MEN1KMT2A | |
| SCHEMBL5304972 | 0.62 | — | — | |
| SCHEMBL11050653 | 0.60 | BRD4 (0.52) | — | |
| SCHEMBL8950260 | 0.60 | BRD4 (0.33) | — | |
| SCHEMBL2514082 | 0.60 | BRD4 (0.33) | — | |
| SCHEMBL181791 | 0.57 | — | — | |
| SCHEMBL5530657 | 0.57 | — | — | |
| SCHEMBL21611711 | 0.57 | — | — | |
| SCHEMBL16359804 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137033-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS | SORACCO RYAN D (US) | 2023-07-20 | — | — | WO | disclosed |
| CN-114848614-A | Heat stable dry powder pharmaceutical compositions and methods | 曼金德公司 | 2022-08-05 | — | — | CN | disclosed |
| US-20210244667-A1 | HEAT-STABLE DRY POWDER PHARMACEUTICAL COMPOSITIONS AND METHODS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2021-08-12 | — | — | US | disclosed |
| US-11013691-B2 | Heat-stable dry powder pharmaceutical compositions and methods | MANNKIND CORPORATION (US) | 2021-05-25 | — | — | US | disclosed |
| US-10413513-B2 | Heat-stable dry powder pharmaceutical compositions and methods | MANNKIND CORPORATION (US) | 2019-09-17 | — | — | US | disclosed |
| US-20180221280-A1 | HEAT-STABLE DRY POWDER PHARMACEUTICAL COMPOSITIONS AND METHODS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2018-08-09 | — | — | US | disclosed |
| US-9925144-B2 | Heat-stable dry powder pharmaceutical compositions and methods | MANNKIND CORPORATION (US) | 2018-03-27 | — | — | US | disclosed |
| US-20160158156-A1 | HEAT-STABLE DRY POWDER PHARMACEUTICAL COMPOSITIONS AND METHODS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2016-06-09 | — | — | US | disclosed |
| EP-3021834-A1 | HEAT-STABLE DRY POWDER PHARMACEUTICAL COMPOSITIONS AND METHODS | MannKind Corporation (US) | 2016-05-25 | — | — | EP | disclosed |
| CN-105451716-A | Heat stable dry powder pharmaceutical compositions and methods | MANNKIND CORP | 2016-03-30 | — | — | CN | disclosed |
| WO-2015010092-A1 | HEAT-STABLE DRY POWDER PHARMACEUTICAL COMPOSITIONS AND METHODS | MANNKIND CORPORATION (US) | 2015-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180221280-A1 | HEAT-STABLE DRY POWDER PHARMACEUTICAL COMPOSITIONS AND METHODS | OXTR, AVPR2, CRH | MEN1 1273/4885NPC1 2903/4885RAB9A 2443/4885 |
| US-20160158156-A1 | HEAT-STABLE DRY POWDER PHARMACEUTICAL COMPOSITIONS AND METHODS | OXTR, AVPR2, CRH | MEN1 1273/4885NPC1 2903/4885RAB9A 2443/4885 |
| US-20210244667-A1 | HEAT-STABLE DRY POWDER PHARMACEUTICAL COMPOSITIONS AND METHODS | OXTR, AVPR2, CRH | MEN1 1273/4885NPC1 2903/4885RAB9A 2443/4885 |
| US-10413513-B2 | Heat-stable dry powder pharmaceutical compositions and methods | OXTR, AVPR2, CRH | MEN1 1273/4885NPC1 2903/4885RAB9A 2443/4885 |
| US-11013691-B2 | Heat-stable dry powder pharmaceutical compositions and methods | OXTR, AVPR2, CRH | MEN1 1273/4885NPC1 2903/4885RAB9A 2443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.