SCHEMBL1640150

SCHEMBL1640150

CCn1c(=O)[nH]c2cc(N)ccc21

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.61
MEN1 O00255 3/20 0.61
CYP1A2 P05177 3/20 0.61
LMNA P02545 2/20 0.61
CYP3A4 P08684 1/20 0.61
CYP2D6 P10635 1/20 0.61
TSHR P16473 1/20 0.61
NFKB1 P19838 1/20 0.61
BLM P54132 1/20 0.61
PMP22 Q01453 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
ALDH1A1 P00352 4/20 0.58
KDM4E B2RXH2 3/20 0.58
MAPT P10636 3/20 0.58
GAA P10253 1/20 0.58
GFER P55789 1/20 0.58
PGR P06401 1/20 0.46
HPGD P15428 1/20 0.45
MAPK1 P28482 1/20 0.45
HTT P42858 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11314894 0.87 MAPT (0.47) KMT2AMEN1CYP1A2LMNACYP3A4
SCHEMBL9807415 0.84 ALDH1A1 (0.51) KMT2AMEN1CYP1A2LMNACYP3A4
SCHEMBL14326956 0.81 KMT2A (0.62) KMT2AMEN1CYP1A2LMNACYP3A4
SCHEMBL10138713 0.80 KMT2A (0.51) KMT2AMEN1CYP1A2LMNACYP3A4
SCHEMBL26040453 0.80 KMT2A (0.60) KMT2AMEN1CYP1A2LMNACYP3A4
SCHEMBL6904502 0.80 CYP1A2 (0.60) KMT2AMEN1CYP1A2LMNACYP3A4
SCHEMBL4077298 0.80 CYP1A2 (0.60) KMT2AMEN1CYP1A2LMNACYP3A4
SCHEMBL6904508 0.80 MEN1 (0.66) KMT2AMEN1CYP1A2LMNACYP3A4
SCHEMBL24993893 0.80 ALDH1A1 (0.40) KMT2AMEN1CYP1A2LMNACYP3A4
SCHEMBL24994421 0.80 CCR4 (0.41) KMT2AMEN1CYP1A2LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110098466-A1 Synthesis Of Triphenodioxazine Pigments CLARIANT FINANCE (BVI) LIMITED (VG) 2011-04-28 US disclosed
WO-2009027014-A2 SYNTHESIS OF TRIPHENODIOXAZINE PIGMENTS CLARIANT INTERNATIONAL LTD (CH) 2009-03-05 WO disclosed
EP-2031026-A1 Synthesis of triphenodioxazine pigments CLARIANT INTERNATIONAL LTD. (CH) 2009-03-04 EP disclosed
US-7307170-B2 Epindolidione pigments CLARIANT FINANCE (BVI) LIMITED (VG) 2007-12-11 US disclosed
US-7307170-B2 Epindolidione pigments CLARIANT FINANCE (BVI) LIMITED (VG) 2007-12-11 US disclosed
US-7262284-B2 Method for producing disazo pigments CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2007-08-28 US disclosed
US-20060167236-A1 Method for producing disazo pigments CLARIANT GMBH (DE) 2006-07-27 US disclosed
EP-1201718-B1 Mixed crystals of benzimidazoloneoxazine derivatives CLARIANT PRODUKTE DEUTSCHLAND (DE) 2006-05-24 EP disclosed
EP-1132432-B1 Preparation process of pigments CLARIANT FINANCE BVI LTD (VG) 2006-02-08 EP disclosed
EP-1517962-A1 METHOD FOR PRODUCING DISAZO PIGMENTS Clariant GmbH (DE) 2005-03-30 EP disclosed
WO-2002046315-A1 PROCESS FOR THE PREPARATION OF TRIPHENODIOXAZINE PIGMENTS CLARIANT FINANCE (BVI) LIMITED (VG) 2002-06-13 WO disclosed
EP-1201718-A2 Mixed crystals of benzimidazoloneoxazine derivatives Clariant GmbH (DE) 2002-05-02 EP disclosed
US-6355795-B1 PIGMENTS POSSESSING HIGH FASTNESS TO SOLVENTS, MIGRATION AND LIGHT, WHICH HAVE GOOD THERMAL STABILITIES AND HIGH TINTING POWER AND ARE ALSO EASILY DISPERSIBLE CLARIANT FINANCE (BVI) LIMITED (BV) 2002-03-12 US disclosed
US-20010031864-A1 Preparation of pigments CLARIANT FINANCE (BVI) LIMITED 2001-10-18 US disclosed
EP-1132432-A2 Preparation process of pigments Clariant Finance (BVI) Limited (VG) 2001-09-12 EP disclosed
EP-1120420-A2 New triphendioxazine compounds Clariant Finance (BVI) Limited (VG) 2001-08-01 EP disclosed
EP-1120421-A2 New triphendioxazine compounds Clariant Finance (BVI) Limited (VG) 2001-08-01 EP disclosed
US-6255482-B1 PREPARING CHLORINE-CONTAINING TRIPHENDIOXAZINE COMPOUNDS USEFUL AS PIGMENTS POSSESSING HIGH FASTNESS TO SOLVENTS, MIGRATION, AND LIGHT, WHICH HAVE GOOD THERMAL STABILITIES AND HIGH TINTING POWER CLARIANT FINANCE (BVI) LIMITED (VG) 2001-07-03 US disclosed
EP-0911337-A1 New triphendioxazine compounds Clariant Finance (BVI) Limited (VG) 1999-04-28 EP disclosed
US-3956266-A DISAZO DYES CIBA-GEIGY CORPORATION (US) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110098466-A1 Synthesis Of Triphenodioxazine Pigments TYR, SCO2, NDUFS5 KMT2A 3089/4885MEN1 3867/4885CYP1A2 104/4885
US-20060167236-A1 Method for producing disazo pigments TYR, IPO4, CBR3 KMT2A 2138/4885MEN1 2054/4885CYP1A2 40/4885
US-20010031864-A1 Preparation of pigments SCO2, PPOX, PRDX4 KMT2A 1664/4885MEN1 216/4885CYP1A2 317/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.