Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16401601 | 0.81 | EPHX1 (0.44) | EPHX1 | |
| SCHEMBL16401633 | 0.81 | HDAC1 (0.52) | EPHX1KMT2A | |
| SCHEMBL16401555 | 0.79 | ACHE (0.43) | EPHX1ACHE | |
| SCHEMBL16401890 | 0.79 | ACHE (0.50) | EPHX1KMT2AACHE | |
| SCHEMBL16401697 | 0.78 | EPHX1 (0.55) | EPHX1KMT2AACHE | |
| SCHEMBL16401565 | 0.76 | HPGD (0.51) | EPHX1 | |
| SCHEMBL16401827 | 0.74 | HDAC1 (0.53) | EPHX1ACHE | |
| SCHEMBL16401891 | 0.73 | CA9 (0.50) | POLBKMT2A | |
| SCHEMBL16401599 | 0.73 | EPHX1 (0.36) | EPHX1 | |
| SCHEMBL16401778 | 0.73 | EPHX1 (0.53) | EPHX1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007613-A1 | O-ALKYL TRIAZOLYL CARBAMATES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-01-22 | — | — | WO | disclosed |