Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16401599 | 0.90 | EPHX1 (0.36) | EPHX1KDM4EALDH1A1TSHRTP53 | |
| SCHEMBL16401633 | 0.84 | HDAC1 (0.52) | EPHX1 | |
| SCHEMBL16401697 | 0.82 | EPHX1 (0.55) | EPHX1ALDH1A1 | |
| SCHEMBL16401574 | 0.81 | EPHX1 (0.39) | EPHX1 | |
| SCHEMBL16401778 | 0.77 | EPHX1 (0.53) | EPHX1ALDH1A1TSHRTP53 | |
| SCHEMBL16401890 | 0.77 | ACHE (0.50) | EPHX1 | |
| SCHEMBL16401827 | 0.75 | HDAC1 (0.53) | EPHX1 | |
| SCHEMBL16401565 | 0.75 | HPGD (0.51) | EPHX1 | |
| SCHEMBL16401690 | 0.75 | MEN1 (0.59) | EPHX1KDM4EALDH1A1 | |
| SCHEMBL16401555 | 0.73 | ACHE (0.43) | EPHX1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007613-A1 | O-ALKYL TRIAZOLYL CARBAMATES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-01-22 | — | — | WO | claimed |
| WO-2015007613-A1 | O-ALKYL TRIAZOLYL CARBAMATES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-01-22 | — | — | WO | disclosed |