Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16401797 | 0.89 | EPHX1 (0.47) | MEN1KMT2APOLBNPC1KDM4E | |
| SCHEMBL16401891 | 0.86 | CA9 (0.50) | MEN1KMT2APOLBNPC1MAPT | |
| SCHEMBL16401697 | 0.83 | EPHX1 (0.55) | MEN1KMT2AALDH1A1EPHX1 | |
| SCHEMBL16401898 | 0.82 | CYP19A1 (0.51) | ALDH1A1EPHX1 | |
| SCHEMBL16401778 | 0.81 | EPHX1 (0.53) | MEN1KMT2ANPC1ALDH1A1EPHX1 | |
| SCHEMBL16401633 | 0.78 | HDAC1 (0.52) | MEN1KMT2AEPHX1CYP1A2CYP2D6 | |
| SCHEMBL16401548 | 0.76 | ALDH1A1 (0.44) | ALDH1A1EPHX1GLA | |
| SCHEMBL16401475 | 0.76 | CYP1A2 (0.47) | MEN1KMT2APOLBNPC1ALDH1A1 | |
| SCHEMBL16401827 | 0.76 | HDAC1 (0.53) | EPHX1 | |
| SCHEMBL31434856 | 0.76 | NPC1 (0.73) | MEN1KMT2APOLBNPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007613-A1 | O-ALKYL TRIAZOLYL CARBAMATES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-01-22 | — | — | WO | claimed |
| WO-2015007613-A1 | O-ALKYL TRIAZOLYL CARBAMATES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-01-22 | — | — | WO | disclosed |