SCHEMBL16401797

SCHEMBL16401797

O=C(NC1CCCCC1)OCCc1cn(-c2ccccc2)nn1

nearest known ligand 0.80

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
POLB P06746 2/20 0.47
NPC1 O15118 1/20 0.46
SLC6A9 P48067 1/20 0.46
ALDH1A1 P00352 2/20 0.45
RAB9A P51151 1/20 0.45
NOTUM Q6P988 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
MAOA P21397 1/20 0.45
GLA P06280 1/20 0.45
MAPT P10636 1/20 0.44
KDM4E B2RXH2 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MIF P14174 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16401690 0.89 MEN1 (0.59) EPHX1MEN1KMT2APOLBNPC1
SCHEMBL16401475 0.87 CYP1A2 (0.47) MEN1KMT2APOLBNPC1SLC6A9
SCHEMBL16401738 0.84 SMN1; SMN2 (0.51) EPHX1ALDH1A1SMN1; SMN2
SCHEMBL16401891 0.76 CA9 (0.50) MEN1KMT2APOLBNPC1RAB9A
SCHEMBL7181896 0.75 EPHX1 (0.60) EPHX1MEN1KMT2ANPC1ALDH1A1
SCHEMBL16401548 0.75 ALDH1A1 (0.44) EPHX1SLC6A9ALDH1A1RAB9AGLA
SCHEMBL16401885 0.74 POLB (0.50) KMT2APOLBALDH1A1KDM4ESMN1; SMN2
SCHEMBL16401778 0.73 EPHX1 (0.53) EPHX1MEN1KMT2ANPC1ALDH1A1
SCHEMBL16403638 0.73 MIF (0.52) MEN1KMT2APOLBNPC1SLC6A9
SCHEMBL16401697 0.72 EPHX1 (0.55) EPHX1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015007613-A1 O-ALKYL TRIAZOLYL CARBAMATES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) 2015-01-22 WO claimed
WO-2015007613-A1 O-ALKYL TRIAZOLYL CARBAMATES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) 2015-01-22 WO disclosed