Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16401690 | 0.76 | MEN1 (0.59) | ALDH1A1GLAEPHX1 | |
| SCHEMBL16401797 | 0.75 | EPHX1 (0.47) | ALDH1A1RAB9AGLAEPHX1SLC6A9 | |
| SCHEMBL14223546 | 0.68 | ALDH1A1 (0.47) | ALDH1A1RAB9AGRM5FAAHTSHR | |
| SCHEMBL9634370 | 0.67 | NOTUM (0.50) | GLA | |
| SCHEMBL16401891 | 0.67 | CA9 (0.50) | RAB9ASMN1; SMN2 | |
| SCHEMBL13119830 | 0.67 | P2RX7 (0.50) | ALDH1A1GLAGAA | |
| SCHEMBL14223545 | 0.66 | ALDH1A1 (0.45) | ALDH1A1RAB9AGRM5FAAHTSHR | |
| SCHEMBL31286268 | 0.66 | NAAA (0.47) | ALDH1A1RAB9AFAAHTSHREPHX1 | |
| SCHEMBL2201239 | 0.66 | ALDH1A1 (0.51) | ALDH1A1RAB9ALMNASMN1; SMN2GAA | |
| SCHEMBL17509955 | 0.66 | NAAA (0.47) | ALDH1A1RAB9AFAAHTSHREPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007613-A1 | O-ALKYL TRIAZOLYL CARBAMATES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-01-22 | — | — | WO | claimed |
| WO-2015007613-A1 | O-ALKYL TRIAZOLYL CARBAMATES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-01-22 | — | — | WO | disclosed |