Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PGD | P52209 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1263837 | 1.00 | TSHR (0.43) | TSHRSRCTP53PGDMMP1 | |
| SCHEMBL1263842 | 0.90 | TSHR (0.47) | TSHRSRCTP53PGDMMP1 | |
| SCHEMBL27928848 | 0.84 | TSHR (0.41) | TSHRTP53MMP1MMP2MMP3 | |
| SCHEMBL9223118 | 0.81 | TSHR (0.39) | TSHRSRCTP53PGDMMP1 | |
| SCHEMBL9213810 | 0.79 | TSHR (0.38) | TSHRSRC | |
| SCHEMBL7516069 | 0.79 | TSHR (0.47) | TSHRSRCTP53PGDMMP1 | |
| SCHEMBL7516079 | 0.79 | TSHR (0.47) | TSHRSRCTP53PGDMMP1 | |
| SCHEMBL18141689 | 0.78 | ALDH1A1 (0.39) | TSHRSRCPGDMMP1MMP2 | |
| SCHEMBL4950263 | 0.77 | TSHR (0.45) | TSHRSRCTP53PGDMMP1 | |
| SCHEMBL1431069 | 0.77 | TSHR (0.45) | TSHRSRCTP53PGDMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007388-A1 | SALTS OF (E)-N-((1S,4S)-4-(DIMETHYLAMINO)-1,4-DIPHENYLCYCLOHEXYL)-N-METHYLCINNAMAMIDE | Grünenthal GmbH (DE) | 2015-01-22 | — | — | WO | disclosed |