Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1263837 | 0.84 | TSHR (0.43) | TSHRTP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL16401951 | 0.84 | TSHR (0.43) | TSHRTP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL21954760 | 0.77 | TSHR (0.38) | TSHRTP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL27805163 | 0.76 | OR51E2 (0.31) | LMNA | |
| SCHEMBL1001815 | 0.73 | PDE4A (0.50) | LMNA | |
| SCHEMBL7114338 | 0.73 | TP53 (0.44) | TSHRTP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2909111 | 0.73 | ALDH1A1 (0.46) | TSHRTP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL28211257 | 0.71 | TP53 (0.42) | TSHRTP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL27484021 | 0.71 | TP53 (0.42) | TSHRTP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9435536 | 0.71 | TP53 (0.38) | TSHRTP53MMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103432091-A | Improved-performance tablet and preparation method thereof | ZHONG SHUGUANG | 2013-12-11 | — | — | CN | claimed |
| CN-102258785-B | Slow-release drug carrier | ZHONG SHUGUANG | 2013-07-24 | — | — | CN | claimed |