Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11050724 | 0.78 | ALDH1A1 (0.58) | ALDH1A1HPGDPKMMAPTKMT2A | |
| SCHEMBL19911369 | 0.76 | ALDH1A1 (0.51) | ALDH1A1HPGDPKMMAPTKMT2A | |
| SCHEMBL16402072 | 0.75 | MEN1 (0.42) | HPGDPKMKMT2ASMN1; SMN2HTT | |
| SCHEMBL15531972 | 0.72 | ALDH1A1 (0.56) | ALDH1A1HPGDPKMMAPTKMT2A | |
| SCHEMBL11797084 | 0.72 | PKM (0.64) | ALDH1A1HPGDPKMMAPTKMT2A | |
| SCHEMBL31304613 | 0.72 | ALDH1A1 (0.56) | ALDH1A1HPGDPKMMAPTKMT2A | |
| SCHEMBL8555984 | 0.71 | PKM (0.61) | ALDH1A1HPGDPKMMAPTKMT2A | |
| SCHEMBL211698 | 0.70 | L3MBTL1 (0.61) | ALDH1A1HPGDPKMMAPTKMT2A | |
| SCHEMBL19911366 | 0.70 | PKM (0.68) | ALDH1A1HPGDPKMMAPTKMT2A | |
| SCHEMBL20985897 | 0.70 | PKM (0.57) | ALDH1A1HPGDPKMMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015009699-A1 | METHODS AND COMPOSITIONS TO PREVENT OR TREAT BACTERIAL INFECTIONS | KETTER PATRICK (US) | 2015-01-22 | — | — | WO | disclosed |