SCHEMBL1640243

SCHEMBL1640243

CCCCCc1cccc(C#N)c1-c1ccccc1-c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.41
NR1H2 P55055 1/20 0.38
NR1H3 Q13133 1/20 0.38
ALOX5 P09917 1/20 0.38
PTGS2 P35354 1/20 0.38
PPARA Q07869 3/20 0.37
TLR8 Q9NR97 1/20 0.36
BID P55957 3/20 0.36
MCL1 Q07820 3/20 0.36
BCL2L1 Q07817 2/20 0.36
BAK1 Q16611 2/20 0.36
KAT8 Q9H7Z6 2/20 0.36
PPARG P37231 1/20 0.36
EP300 Q09472 1/20 0.36
KAT2A Q92830 1/20 0.36
KAT2B Q92831 1/20 0.36
KAT5 Q92993 1/20 0.36
SAE1 Q9UBE0 1/20 0.36
KDM4E B2RXH2 1/20 0.36
GALR3 O60755 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8634020 0.99 LIPG (0.43) LIPGNR1H2NR1H3ALOX5PTGS2
SCHEMBL27328036 0.89 LIPG (0.45) LIPGALOX5PTGS2PPARABID
SCHEMBL27310239 0.87 LIPG (0.47) LIPGPPARABIDMCL1BCL2L1
SCHEMBL27836089 0.81 PDCD1 (0.44) LIPGNR1H2NR1H3ALOX5PTGS2
SCHEMBL978626 0.81 LIPG (0.50) LIPGNR1H2NR1H3ALOX5PTGS2
SCHEMBL365486 0.80 CD274 (0.44) LIPGNR1H2NR1H3PPARATLR8
SCHEMBL5925417 0.80 TSHR (0.50) LIPGNR1H2NR1H3PPARATLR8
SCHEMBL4257929 0.80 TSHR (0.50) PPARGALDH1A1HPGD
SCHEMBL11296054 0.79 DHFR (0.47) LIPGNR1H2NR1H3ALOX5PTGS2
SCHEMBL3629719 0.79 LIPG (0.53) LIPGNR1H2NR1H3PPARABID

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9028290-B2 Method of producing polymer dispersed liquid crystal device using cooling plate DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2015-05-12 US disclosed
US-20140065917-A1 METHOD OF PRODUCING POLYMER DISPERSED LIQUID CRYSTAL DEVICE USING COOLING PLATE DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2014-03-06 US disclosed
US-8323221-B2 Tissue temperature indicating element for ultrasound therapy KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2012-12-04 US disclosed
US-20110098609-A1 TISSUE TEMPERATURE INDICATING ELEMENT FOR ULTRASOUND THERAPY KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2011-04-28 US disclosed
EP-2219735-A2 TISSUE TEMPERATURE INDICATING ELEMENT FOR ULTRASOUND THERAPY Koninklijke Philips Electronics N.V. (NL) 2010-08-25 EP disclosed
US-20090264308-A1 BIOSENSOR SOLID SUBSTRATE WITH INTEGRATED TEMPERATURE CONTROL AND A METHOD TO MAKE THE SAME KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2009-10-22 US disclosed
WO-2009063399-A2 TISSUE TEMPERATURE INDICATING ELEMENT FOR ULTRASOUND THERAPY KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2009-05-22 WO disclosed
EP-2029280-A1 A BIOSENSOR SOLID SUBSTRATE WITH INTEGRATED TEMPERATURE CONTROL AND A METHOD TO MAKE THE SAME Koninklijke Philips Electronics N.V. (NL) 2009-03-04 EP disclosed
US-7335405-B2 Nematic liquid crystal mixtures for use in bistable display devices NEMOPTIC (FR) 2008-02-26 US disclosed
CN-100368836-C Polymer dispersed liquid crystal optical attenuator array and its production method UNIV JILIN (CN) 2008-02-13 CN disclosed
CN-100367082-C MEMS liquid crystal light attenuator array and producing method thereof UNIV JILIN (CN) 2008-02-06 CN disclosed
WO-2007135651-A1 A BIOSENSOR SOLID SUBSTRATE WITH INTEGRATED TEMPERATURE CONTROL AND A METHOD TO MAKE THE SAME KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2007-11-29 WO disclosed
US-20060249708-A1 Nematic liquid crystal mixtures for use in bistable display devices CDC PROPRIETE INTELLECTUELLE (FR) 2006-11-09 US disclosed
US-7115307-B2 Nematic liquid crystal mixtures for bistable display device NEMOPTIC (FR) 2006-10-03 US disclosed
CN-1828350-A Polymer dispersed liquid crystal optical attenuator array and its production method UNIV JILIN (CN) 2006-09-06 CN disclosed
CN-1811528-A MEMS liquid crystal light attenuator array and producing method thereof UNIV JILIN (CN) 2006-08-02 CN disclosed
US-20040188654-A1 Nematic liquid crystal mixtures for bistable display devices CDC PROPRIETE INTELLECTUELLE (FR) 2004-09-30 US disclosed