SCHEMBL16402904

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16402903	1.00	CHEK1 (0.40)	CHEK1USP7TRPV1PIM1PIM2
	SCHEMBL16402950	0.87	NFE2L2 (0.39)	MEN1KMT2ACTSSCTSKALDH1A1
	SCHEMBL16399133	0.87	NFE2L2 (0.39)	MEN1KMT2ACTSSCTSKALDH1A1
	SCHEMBL16398797	0.85	CHEK1 (0.39)	CHEK1USP7TRPV1PIM1PIM2
	SCHEMBL16398795	0.85	CHEK1 (0.39)	CHEK1USP7TRPV1PIM1PIM2
	SCHEMBL16399625	0.82	ERBB2 (0.43)	CHEK1USP7TRPV1PIM1PIM2
	SCHEMBL16399627	0.82	ERBB2 (0.43)	CHEK1USP7TRPV1PIM1PIM2
	SCHEMBL16399373	0.81	AHR (0.40)	NOTUMMEN1KMT2AALDH1A1
	SCHEMBL17969056	0.81	AHR (0.40)	NOTUMMEN1KMT2AALDH1A1
	SCHEMBL16402744	0.79	NQO2 (0.36)	USP7TRPA1SCN5ASCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.