Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16402964 | 0.89 | ALDH1A1 (0.34) | ALDH1A1LMNAGRIN2BKDM4EMMP1 | |
| SCHEMBL144742 | 0.84 | GRIN2B (0.42) | ALDH1A1GRIN2BKDM4EMMP1 | |
| SCHEMBL146713 | 0.81 | GRIN2B (0.33) | ALDH1A1LMNAGRIN2BCYP3A4CYP2C9 | |
| SCHEMBL16402974 | 0.80 | GRIN2B (0.36) | ALDH1A1LMNAGRIN2BKDM4EMMP1 | |
| SCHEMBL22776384 | 0.78 | ABCB1 (0.39) | GRIN2BCTSLCTSBCTSK | |
| SCHEMBL16400539 | 0.78 | GRIN2B (0.35) | ALDH1A1LMNAGRIN2BKDM4EMMP1 | |
| SCHEMBL143089 | 0.74 | GRIN2B (0.42) | ALDH1A1GRIN2BKDM4EMMP1CYP3A4 | |
| SCHEMBL3402984 | 0.74 | GRIN2B (0.42) | ALDH1A1GRIN2BKDM4EMMP1CYP3A4 | |
| SCHEMBL141744 | 0.71 | GRIN2B (0.32) | ALDH1A1LMNAGRIN2BMEN1KMT2A | |
| SCHEMBL1273271 | 0.70 | MMP1 (0.42) | MMP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004084-B1 | SUBSTITUTED BENZOXAZOLES | Bayer Pharma AG (DE) | 2017-03-01 | — | — | EP | disclosed |
| EP-3004084-A1 | SUBSTITUTED BENZOXAZOLES | Bayer Pharma Aktiengesellschaft (DE) | 2016-04-13 | — | — | EP | disclosed |
| WO-2014195231-A1 | SUBSTITUTED BENZOXAZOLES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-12-11 | — | — | WO | disclosed |