Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 7/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404071 | 0.91 | RAB9A (0.40) | ALDH1A1KDM4ERAB9APOLBGAA | |
| SCHEMBL14224988 | 0.88 | RAB9A (0.41) | ALDH1A1KDM4ERAB9APOLBGAA | |
| SCHEMBL16404150 | 0.88 | RAB9A (0.42) | ALDH1A1KDM4ERAB9APOLBGAA | |
| SCHEMBL14224958 | 0.86 | ALDH1A1 (0.43) | ALDH1A1KDM4ERAB9APOLBGAA | |
| SCHEMBL16403981 | 0.85 | RAB9A (0.43) | ALDH1A1KDM4ERAB9APOLBGAA | |
| SCHEMBL14224974 | 0.84 | ALDH1A1 (0.39) | ALDH1A1KDM4ERAB9APOLBGAA | |
| SCHEMBL14325787 | 0.82 | RAB9A (0.50) | ALDH1A1KDM4ERAB9APOLBNPC1 | |
| SCHEMBL16403987 | 0.81 | RAB9A (0.50) | ALDH1A1RAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL14325805 | 0.80 | RAB9A (0.39) | ALDH1A1KDM4ERAB9APOLBGAA | |
| SCHEMBL16403954 | 0.78 | HDAC1 (0.35) | ALDH1A1KDM4ERAB9APOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937065-B2 | Compositions and methods for modulating a kinase | CLEVEXEL PHARMA (FR) | 2015-01-20 | — | — | US | disclosed |