Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14325787 | 0.93 | RAB9A (0.50) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL16404071 | 0.81 | RAB9A (0.40) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16403920 | 0.81 | ALDH1A1 (0.38) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16404150 | 0.80 | RAB9A (0.42) | RAB9ANPC1MEN1KMT2AMAPK1 | |
| SCHEMBL14684730 | 0.80 | ATP4A (0.43) | RAB9ANPC1MEN1KMT2AMAPK1 | |
| SCHEMBL14224988 | 0.79 | RAB9A (0.41) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14224974 | 0.77 | ALDH1A1 (0.39) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14224958 | 0.77 | ALDH1A1 (0.43) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16403981 | 0.76 | RAB9A (0.43) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14684744 | 0.76 | RAB9A (0.50) | RAB9ANPC1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937065-B2 | Compositions and methods for modulating a kinase | CLEVEXEL PHARMA (FR) | 2015-01-20 | — | — | US | disclosed |
| US-8937065-B2 | Compositions and methods for modulating a kinase | CLEVEXEL PHARMA (FR) | 2015-01-20 | — | — | US | disclosed |