Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14325852 | 0.85 | NPC1 (0.66) | NPC1MEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL16404120 | 0.83 | NPC1 (0.63) | NPC1MEN1KMT2ALMNAHTT | |
| SCHEMBL16403952 | 0.83 | NPC1 (0.57) | NPC1MEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL16403943 | 0.81 | RAB9A (0.47) | NPC1MEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL16404114 | 0.81 | NPC1 (0.52) | NPC1MEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL14317616 | 0.79 | NPC1 (0.52) | NPC1MEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL14318297 | 0.78 | LMNA (0.51) | NPC1MEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL16403951 | 0.78 | RAB9A (0.47) | NPC1MEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL16403946 | 0.78 | BLM (0.50) | NPC1MEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL14315440 | 0.78 | BLM (0.51) | NPC1MEN1KMT2ARAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937065-B2 | Compositions and methods for modulating a kinase | CLEVEXEL PHARMA (FR) | 2015-01-20 | — | — | US | disclosed |
| US-8937065-B2 | Compositions and methods for modulating a kinase | CLEVEXEL PHARMA (FR) | 2015-01-20 | — | — | US | disclosed |