Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16403964 | 0.93 | KDM4E (0.49) | RAB9AALDH1A1NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL16403917 | 0.91 | KDM4E (0.53) | RAB9AALDH1A1NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL14325734 | 0.89 | KDM4E (0.64) | RAB9AALDH1A1NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL16403922 | 0.88 | KDM4E (0.61) | RAB9AALDH1A1NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL16403932 | 0.88 | ALDH1A1 (0.45) | RAB9AALDH1A1NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL16404129 | 0.86 | KDM4E (0.47) | RAB9AALDH1A1NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL14325737 | 0.86 | RAB9A (0.63) | RAB9AALDH1A1NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL14684741 | 0.86 | ALDH1A1 (0.42) | RAB9AALDH1A1NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL14224952 | 0.84 | KDM4E (0.44) | RAB9AALDH1A1NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL16404165 | 0.84 | KDM4E (0.44) | RAB9AALDH1A1NPC1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937065-B2 | Compositions and methods for modulating a kinase | CLEVEXEL PHARMA (FR) | 2015-01-20 | — | — | US | disclosed |