Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.68 |
| ▸ | POLB | P06746 | 5/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.62 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL9956778 | 0.95 | TDP1 (0.63) | TDP1MAPK1POLBL3MBTL1RECQL | |
| SCHEMBL8923884 | 0.88 | TDP1 (0.62) | TDP1MAPK1POLBL3MBTL1RECQL | |
| SCHEMBL10036470 | 0.88 | TDP1 (0.66) | TDP1MAPK1POLBL3MBTL1RECQL | |
| SCHEMBL13264390 | 0.82 | ALDH1A1 (0.61) | TDP1MAPK1POLBL3MBTL1RECQL | |
| SCHEMBL6443452 | 0.82 | ALDH1A1 (0.70) | TDP1MAPK1POLBL3MBTL1RECQL | |
| SCHEMBL16690062 | 0.82 | TDP1 (0.67) | TDP1MAPK1POLBL3MBTL1ALDH1A1 | |
| SCHEMBL13433782 | 0.81 | TDP1 (0.58) | TDP1MAPK1POLBL3MBTL1RECQL | |
| SCHEMBL27939896 | 0.81 | TDP1 (0.58) | TDP1MAPK1POLBL3MBTL1ALDH1A1 | |
| SCHEMBL179961 | 0.81 | ALDH1A1 (0.64) | TDP1MAPK1POLBALDH1A1KMT2A | |
| SCHEMBL18539435 | 0.80 | KMT2A (0.57) | TDP1MAPK1POLBL3MBTL1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110612119-A | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents | 西雅图儿童医院（DBA西雅图儿童研究所） | 2019-12-24 | — | — | CN | claimed |
| WO-2018148224-A1 | PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS | Seattle Children's Hospital (dba Seattle Children's Research Institute) (US) | 2018-08-16 | — | — | WO | claimed |
| WO-2013013829-A1 | HEALABLE COMPOSITE MATERIALS BASED ON REVERSIBLE BINDER SYSTEMS | EADS DEUTSCHLAND GMBH (DE) | 2013-01-31 | — | — | WO | claimed |
| EP-2551093-A1 | Healable composite materials based on reversible binder systems | EADS Deutschland GmbH (DE) | 2013-01-30 | — | — | EP | claimed |
| US-6872754-B1 | Method for processing elastomers | WORTHAM LEON (US) | 2005-03-29 | — | — | US | claimed |
| EP-0795596-B1 | Fuel compositions | SHELL INT RESEARCH (NL) | 2000-10-11 | — | — | EP | claimed |
| EP-0795596-A1 | Fuel compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1997-09-17 | — | — | EP | claimed |
| CN-110612119-B | Phosphatidylether (PLE) CAR T cell tumor targeting (CTCT) agents | 西雅图儿童医院（DBA西雅图儿童研究所） | 2024-10-29 | — | — | CN | disclosed |
| US-20240226160-A9 | ACTIVITY-INDUCIBLE FUSION PROTEINS HAVING A HEAT SHOCK PROTEIN 90 BINDING DOMAIN | SEATTLE CHILDREN'S HOSPITAL D/B/A SEATTLE CHILDREN'S RESEARCH INSTITUTE (US) | 2024-07-11 | — | — | US | disclosed |
| US-20240210288-A1 | Representative Diagnostics | VENTANA MED SYST INC (US) | 2024-06-27 | — | — | US | disclosed |
| US-20240131072-A1 | ACTIVITY-INDUCIBLE FUSION PROTEINS HAVING A HEAT SHOCK PROTEIN 90 BINDING DOMAIN | SEATTLE CHILDREN'S HOSPITAL D/B/A SEATTLE CHILDREN'S RESEARCH INSTITUTE (US) | 2024-04-25 | — | — | US | disclosed |
| US-11959838-B2 | Representative diagnostics | VENTANA MEDICAL SYSTEMS, INC. (US) | 2024-04-16 | — | — | US | disclosed |
| EP-4291571-A2 | ACTIVITY-INDUCIBLE FUSION PROTEINS HAVING A HEAT SHOCK PROTEIN 90 BINDING DOMAIN | Seattle Children's Hospital d/b/a Seattle Children's Research Institute (US) | 2023-12-20 | — | — | EP | disclosed |
| WO-2006010087-A1 | ROLLER FOR PROVIDING BENEFITS TO FABRIC | THE PROCTER & GAMBLE COMPANY (US) | 2006-01-26 | — | — | WO | disclosed |
| US-20060005333-A1 | Roller for providing benefits to fabric | PROCTER & GAMBLE COMPANY, THE | 2006-01-12 | — | — | US | disclosed |
| US-20050288506-A1 | SYNTHESIS OF ORGANOMETALLIC CYCLOMETALLATED GROUP VIIIB METAL COMPLEXES | EASTMAN KODAK COMPANY | 2005-12-29 | — | — | US | disclosed |
| US-6872754-B1 | Method for processing elastomers | WORTHAM LEON (US) | 2005-03-29 | — | — | US | disclosed |
| EP-0795596-B1 | Fuel compositions | SHELL INT RESEARCH (NL) | 2000-10-11 | — | — | EP | disclosed |
| US-5925152-A | MIXTURE CONTAINING A FUEL ADDITIVE FURAN DERIVATIVE HAVING HETEROCYCLIC AND/OR ARYL CARBOCYCLIC GROUPS; ANTIDEPOSIT AGENTS, ANTIKNOCK COMPOUNDS | SHELL OIL COMPANY (US) | 1999-07-20 | — | — | US | disclosed |
| EP-0795596-A1 | Fuel compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1997-09-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288506-A1 | SYNTHESIS OF ORGANOMETALLIC CYCLOMETALLATED GROUP VIIIB METAL COMPLEXES | SOD1, COX5B, TBCB | TDP1 4466/4885MAPK1 4063/4885POLB 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.