Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404232 | 0.80 | CNR2 (0.56) | KDM4EALDH1A1CNR2LMNAMAPT | |
| SCHEMBL4958156 | 0.76 | PKM (0.69) | KDM4ELMNACYP2D6SMN1; SMN2KMT2A | |
| SCHEMBL16404204 | 0.71 | CNR1 (0.67) | KDM4EALDH1A1CNR2MAPTL3MBTL1 | |
| SCHEMBL16404246 | 0.71 | CNR1 (0.61) | KDM4EALDH1A1CNR2LMNAMAPT | |
| SCHEMBL4958152 | 0.70 | TSHR (0.54) | KDM4EALDH1A1LMNAMAPK1NPC1 | |
| SCHEMBL28499436 | 0.70 | KDM4E (0.66) | KDM4EALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL1640848 | 0.70 | CNR2 (0.50) | KDM4EALDH1A1CNR2LMNAMAPT | |
| SCHEMBL16404198 | 0.70 | CNR2 (0.55) | ALDH1A1CNR2LMNAMAPTMAPK1 | |
| SCHEMBL24004514 | 0.69 | SMN1; SMN2 (0.63) | KDM4EALDH1A1CNR2LMNAMAPT | |
| SCHEMBL28492426 | 0.68 | GRM5 (0.60) | KDM4EALDH1A1MAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |