Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.47 |
| ▸ | CNR2 | P34972 | 5/20 | 0.47 |
| ▸ | HTR2A | P28223 | 11/20 | 0.43 |
| ▸ | HTR2C | P28335 | 11/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.43 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404245 | 0.89 | CNR2 (0.60) | CNR1CNR2HTR2AHTR2CSLC6A4 | |
| SCHEMBL16404424 | 0.84 | CNR2 (0.55) | CNR1CNR2HTR2AHTR2CSLC6A4 | |
| SCHEMBL16404194 | 0.76 | CNR2 (0.52) | CNR1CNR2HTR2AHTR2CSLC6A4 | |
| SCHEMBL16404191 | 0.75 | CNR2 (0.59) | CNR1CNR2 | |
| SCHEMBL16404217 | 0.72 | CNR2 (0.75) | CNR1CNR2GRM5 | |
| SCHEMBL16404434 | 0.72 | CNR2 (0.70) | CNR1CNR2HTR2AHTR2CSLC6A4 | |
| SCHEMBL4958802 | 0.68 | ALDH1A1 (0.57) | GRM5PDE4DTHRB | |
| SCHEMBL16404254 | 0.63 | CNR1 (0.56) | CNR1CNR2 | |
| SCHEMBL12720363 | 0.60 | CNR2 (0.56) | CNR1CNR2 | |
| SCHEMBL1078126 | 0.60 | HTR2A (1.00) | HTR2AHTR2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |