SCHEMBL16405264

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22353278	0.91	PTGS1 (0.65)	PTGS1PTGS2MGLLFAAHALDH1A1
	SCHEMBL29044909	0.89	MGLL (0.54)	PTGS1PTGS2MGLLFAAHALDH1A1
	SCHEMBL16405262	0.89	MGLL (0.54)	PTGS1PTGS2MGLLFAAHALDH1A1
	SCHEMBL17972723	0.87	PTGS1 (0.50)	PTGS1PTGS2MGLLFAAHALDH1A1
	SCHEMBL2222522	0.85	PTGS1 (0.89)	PTGS1PTGS2MGLLFAAHALDH1A1
	SCHEMBL20621983	0.83	MGLL (0.70)	PTGS1PTGS2MGLLFAAHALDH1A1
	SCHEMBL29064048	0.83	PTGS1 (0.64)	PTGS1PTGS2MGLLFAAHALDH1A1
	SCHEMBL16274103	0.83	MGLL (0.65)	PTGS1PTGS2MGLLFAAHALDH1A1
	SCHEMBL13543586	0.83	MGLL (0.70)	PTGS1PTGS2MGLLFAAHALDH1A1
	SCHEMBL17570363	0.83	PTGS1 (0.48)	PTGS1PTGS2MGLLFAAHALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.