Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.50 |
| ▸ | MGLL | Q99685 | 7/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16405264 | 0.87 | PTGS1 (0.63) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL22353278 | 0.82 | PTGS1 (0.65) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL14868075 | 0.81 | MGLL (0.68) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL14868080 | 0.81 | MGLL (0.68) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL14962677 | 0.81 | MGLL (0.68) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL13078197 | 0.81 | MGLL (0.68) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL14868081 | 0.80 | NAMPT (0.44) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL21648875 | 0.80 | PTGS1 (0.45) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL406101 | 0.79 | MGLL (0.67) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL23870259 | 0.78 | PTGS1 (0.44) | PTGS1PTGS2MGLLFAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067650-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. | 2024-02-29 | — | — | US | disclosed |
| US-11691997-B2 | Macrocycles | LUMIPHORE, INC. (US) | 2023-07-04 | — | — | US | disclosed |
| US-20180194766-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. | 2018-07-12 | — | — | US | disclosed |
| US-20170360956-A1 | FUNCTIONALIZED LINEAR LIGANDS AND COMPLEXES THEREOF | LUMIPHORE, INC. | 2017-12-21 | — | — | US | disclosed |
| US-20170183365-A1 | MACROCYCLES | LUMIPHORE, INC. | 2017-06-29 | — | — | US | disclosed |
| US-20160221971-A1 | DI-MACROCYCLES | LUMIPHORE, INC. (US) | 2016-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160221971-A1 | DI-MACROCYCLES | DLD, NDC1, MCL1 | PTGS1 4176/4885PTGS2 3369/4885MGLL 4429/4885 |
| US-20170360956-A1 | FUNCTIONALIZED LINEAR LIGANDS AND COMPLEXES THEREOF | CLTB, CLTA, EPCAM | PTGS1 4772/4885PTGS2 4801/4885MGLL 4149/4885 |
| US-11691997-B2 | Macrocycles | HCCS, ABCB7, AURKAIP1 | PTGS1 3676/4885PTGS2 2934/4885MGLL 4548/4885 |
| US-20240067650-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | TFRC, CLTC, SLC39A3 | PTGS1 3791/4885PTGS2 3683/4885MGLL 4377/4885 |
| US-20180194766-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | TFRC, CLTC, SLC39A3 | PTGS1 3791/4885PTGS2 3683/4885MGLL 4377/4885 |
| US-20170183365-A1 | MACROCYCLES | HCCS, ABCB7, AURKAIP1 | PTGS1 3676/4885PTGS2 2934/4885MGLL 4548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.